Merck
Todas las fotos(3)

A7219

Sigma-Aldrich

L-Aspartic acid

from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%

Sinónimos:
(S)-Aminobutanedioic acid, (S)-(+)-Aminosuccinic acid
Fórmula lineal:
HO2CCH2CH(NH2)CO2H
Número de CAS:
Peso molecular:
133.10
Beilstein:
1723530
Número de EC:
Número MDL:
eCl@ss:
32160406
ID de la sustancia en PubChem:
NACRES:
NA.75

Nivel de calidad

300

origen biológico

non-animal source

Agency

meets EP testing specifications
meets USP testing specifications

ensayo

98.5-101.0%

formulario

powder

technique(s)

cell culture | mammalian: suitable

impurezas

endotoxin, tested

color

white to off-white

mp

>300 °C (dec.) (lit.)

solubilidad

1 M HCl: 100 mg/mL

SMILES string

N[C@@H](CC(O)=O)C(O)=O

InChI

1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m0/s1

InChI key

CKLJMWTZIZZHCS-REOHCLBHSA-N

Gene Information

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Categorías relacionadas

Envase

100 g in poly bottle
1 kg in poly bottle

Acciones bioquímicas o fisiológicas

Principal neurotransmitter for fast synaptic excitation.

Código de clase de almacenamiento

11 - Combustible Solids

WGK

WGK 1

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Equipo de protección personal

dust mask type N95 (US), Eyeshields, Gloves

Certificado de Análisis

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Certificado de origen

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Florinda Meléndez-Rodríguez et al.
Cell reports, 26(9), 2257-2265 (2019-02-28)
Cellular aspartate drives cancer cell proliferation, but signaling pathways that rewire aspartate biosynthesis to control cell growth remain largely unknown. Hypoxia-inducible factor-1α (HIF1α) can suppress tumor cell proliferation. Here, we discovered that HIF1α acts as a direct repressor of aspartate
Hongyu Ding et al.
Science advances, 7(47), eabk1023-eabk1023 (2021-11-18)
[Figure: see text].
Florinda Meléndez-Rodríguez et al.
Cell reports, 26(9), 2257-2265 (2019-02-28)
Cellular aspartate drives cancer cell proliferation, but signaling pathways that rewire aspartate biosynthesis to control cell growth remain largely unknown. Hypoxia-inducible factor-1α (HIF1α) can suppress tumor cell proliferation. Here, we discovered that HIF1α acts as a direct repressor of aspartate
Thomas Bertero et al.
Cell metabolism, 29(1), 124-140 (2018-10-09)
Dysregulation of extracellular matrix (ECM) deposition and cellular metabolism promotes tumor aggressiveness by sustaining the activity of key growth, invasion, and survival pathways. Yet mechanisms by which biophysical properties of ECM relate to metabolic processes and tumor progression remain undefined.
Shota Someya et al.
iScience, 24(2), 102090-102090 (2021-02-23)
Human pluripotent stem cells (hPSCs) have a unique metabolic signature for maintenance of pluripotency, self-renewal, and survival. Although hPSCs could be potentially used in regenerative medicine, the prohibitive cost associated with large-scale cell culture presents a major barrier to the

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