A7506

L-Ascorbic acid

reagent grade, crystalline

• Sinónimos: Antiscorbutic factor, Vitamin C, L-Threoascorbic acid
• Empirical Formula (Hill Notation): C₆H₈O₆
• Número de CAS: 50-81-7
• Peso molecular: 176.12
• Beilstein: 84272
• Número de EC: 200-066-2
• Número MDL: MFCD00064328
• ID de la sustancia en PubChem: 24891246
• NACRES: NA.26

Propiedades

• Nivel de calidad: 200
• origen biológico: synthetic
• grado: reagent grade
• ensayo: ≥98% ( with iodine, titration)
• formulario: crystalline
• technique(s): HPLC: suitable; cell culture | stem cell: suitable
• color: white to slightly yellow
• pH: 1.0-2.5 (25 °C, 176 g/L in water)
• mp: 190-194 °C (dec.)
• solubilidad: water: soluble 50 mg/mL
• temp. de almacenamiento: room temp
• SMILES string: OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O
• InChI: 1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1
• InChI key: CIWBSHSKHKDKBQ-JLAZNSOCSA-N
• Gene Information: human ... SLC23A2(9962)

Descripción

Descripción general

L-Ascorbic acid biosynthetic pathway varies in plants, animals and fungi. It is synthesized from L-gulono-1,4-lactone by the action of enzyme L-gulono-1,4-lactone oxidase (GLO).

Aplicación

L-Ascorbic acid has been used:

• as a chondrogenic medium component for culturing bone-derived mesenchymal stem cells (BMSCs)(149)
• as a reference standard in high-performance liquid chromatography system (HPLC)(150)
• to test its effect on human gastric cancer GES-1 and AGS cells(151)

Envase

25, 100, 500 g in poly bottle

1 kg in poly bottle

5 kg in poly drum

Acciones bioquímicas o fisiológicas

L-Ascorbic acid deficiency is associated with lack of L-gulono-1,4-lactone oxidase (GLO) enzyme. It elicits antioxidant functionality and gets oxidized to dehydroascorbate via ascorbyl radical intermediate. L-Ascorbic acid is essential for maintaining the redox balance. It is a cofactor for dopamine-β-hydroxylase and favors T cell proliferation, protects immune system and provides relief in common cold.

Ascorbic Acid, also known as Vitamin C, is a six-carbon lactone produced by plants and some animal species but not by humans and other primates. Ascorbic acid functions as an enzymatic cofactor for multiple enzymes, serving as an electron donor for monooxygenases and dioxygenases. Ascorbic acid also functions as a powerful antioxidant, particularly in regards to reactive oxygen species.

Precaución

May darken in storage.

Información de seguridad

• Código de clase de almacenamiento: 13 - Non Combustible Solids
• WGK: WGK 1
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)