B7283

Benserazide hydrochloride

≥98% (HPLC), solid

• Synonym(s): DL-Serine 2-(2,3,4-trihydroxybenzyl)hydrazide hydrochloride
• Empirical Formula (Hill Notation): C₁₀H₁₅N₃O₅ · HCl
• CAS Number: 14919-77-8
• Molecular Weight: 293.70
• Número de EC: 238-991-9
• Número MDL: MFCD00078571
• ID de la sustancia en PubChem: 24277886
• NACRES: NA.77

Properties

• origen biológico: synthetic
• Nivel de calidad: 100
• ensayo: ≥98% (HPLC)
• formulario: solid
• solubilidad: H₂O: 10 mg/mL
• emisor: Roche
• temp. de almacenamiento: room temp
• SMILES string: Cl.NC(CO)C(=O)NNCc1ccc(O)c(O)c1O
• InChI: 1S/C10H15N3O5.ClH/c11-6(4-14)10(18)13-12-3-5-1-2-7(15)9(17)8(5)16;/h1-2,6,12,14-17H,3-4,11H2,(H,13,18);1H
• InChI key: ULFCBIUXQQYDEI-UHFFFAOYSA-N
• Gene Information: human ... DDC(1644)

Description

Descripción general

Benserazide is a peripheral decarboxylase inhibitor.

Aplicación

Benserazide has been used:

• to inhibit dopa-decarboxylase
• to induce dyskinesia
• to test on purified bacterial TDCs to assess the extent to which it could affect bacterial decarboxylases
• as a peripheral dopa decarboxylase inhibitor to treat mice

Envase

1, 5 g

Acciones bioquímicas o fisiológicas

Benserazide can block HK2 enzymatic activity in vitro. It is used along with levodopa to treat Parkinson′s disease.

Inhibitor of L-aromatic amino acid decarboxylase.

Características y beneficios

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety Information

• pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H315 - H319 - H335
• Consejos de prudencia: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Clasificaciones de peligro: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Órganos de actuación: Respiratory system
• Código de clase de almacenamiento: 11 - Combustible Solids
• WGK: WGK 2
• Punto de inflamabilidad F: Not applicable
• Punto de inflamabilidad C: Not applicable
• Equipo de protección personal: dust mask type N95 (US), Eyeshields, Gloves