The solution stability of this product has not been determined. However, an identical product, 219557, notes that solutions prepared in organic solvents, such as acetone, may be stored protected from light at -20°C for up to 3 months. It is recommended that aqueous solutions not be stored for more than 1 day.
C2389
Cerulenin
from Cephalosporium caerulens, ≥98% (HPLC), powder, de novo phospholipid synthesis inhibitor
Sinónimos:
Helicocerin, (2R,3S,E,E)-2,3-Epoxy-4-oxo-7,10-dodecadienamide
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5 MG
MXP 3,465.00
10 MG
MXP 7,602.00
50 MG
MXP 26,426.00
Acerca de este artículo
Fórmula empírica (notación de Hill):
C12H17NO3
Número CAS:
Peso molecular:
223.27
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
EC Number:
241-424-8
MDL number:
Beilstein/REAXYS Number:
4140423
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Permítanos ayudarleNombre del producto
Cerulenin, ≥98% (HPLC), from Cephalosporium caerulens
InChI key
PTNNGEBMCNMENY-JIVMHGEESA-N
InChI
1S/C13H18O3/c1-3-4-5-6-7-8-9-11(15)13-12(16-13)10(2)14/h3-4,6-7,12-13H,5,8-9H2,1-2H3/b4-3+,7-6+/t12-,13+/m0/s1
SMILES string
C/C=C/C/C=C/CCC([C@@H]1[C@H](C(N)=O)O1)=O
biological source
Cephalosporium caerulens
assay
≥98% (HPLC)
form
powder
mp
93 °C
solubility
acetone: 19.60-20.40 mg/mL, clear to slightly hazy, colorless to yellow
antibiotic activity spectrum
fungi
mode of action
enzyme | inhibits
storage temp.
−20°C
Quality Level
Gene Information
human ... FASN(2194)
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Categorías relacionadas
1 of 4
Este artículo | S8559 | G2536 | T7402 |
|---|---|---|---|
| assay ≥98% (HPLC) | assay 95% (HPLC) | assay ≥99% (HPLC) | assay ≥95% (HPLC) |
| form powder | form powder | form powder | form powder |
| Quality Level 200 | Quality Level 200 | Quality Level 300 | Quality Level 200 |
| storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility acetone: 19.60-20.40 mg/mL, clear to slightly hazy, colorless to yellow | solubility H2O: complete 20 mg/ml, clear, colorless to light yellow, H2O: soluble | solubility 0.1 M HCl: 10 mg/mL | solubility DMSO: 50 mg/mL (can be stored frozen for several months), methanol: soluble 50 mg/mL, clear, colorless (undergoes transesterification) |
| biological source Cephalosporium caerulens | biological source - | biological source - | biological source Taxus brevifolia |
Application
Cerulenin has been used:
- as a fatty acid synthase inhibitor to study its effects on aldosterone-induced trained immunity[1]
- as a blocker of fatty acid synthase to study its effects on the replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV2)[2]
- as a supplement in yeast extract–peptone–dextrose/glycerol (YPD/G) agar plates for the isolation of cerulenin-resistant yeast strains[3]
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HOW LONG IS CERULENIN STABLE FOR WHEN DISSOLVED IN ACETONE?
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