Merck
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C2618

Sigma-Aldrich

Cytochalasin D

Ready Made Solution, from Zygosporium mansonii, 5 mg/mL in DMSO

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Sinónimos:
Zygosporin A
Empirical Formula (Hill Notation):
C30H37NO6
Número de CAS:
22144-77-0
Peso molecular:
507.62
Beilstein:
1632828
Número MDL:
MFCD00077706
ID de la sustancia en PubChem:
329775013
NACRES:
NA.85

Nivel de calidad

300

origen biológico

Zygosporium mansonii

formulario

solution

concentración

5 mg/mL in DMSO

espectro de actividad antibiótica

fungi

Modo de acción

enzyme | interferes

enviado en

wet ice

temp. de almacenamiento

−20°C

SMILES string

[H][C@@]12[C@H](C)C(=C)[C@@H](O)[C@@H]3\C=C\C[C@H](C)C(=O)[C@](C)(O)\C=C\[C@@H](OC(C)=O)[C@@]13C(=O)N[C@H]2Cc4ccccc4

InChI

1S/C30H37NO6/c1-17-10-9-13-22-26(33)19(3)18(2)25-23(16-21-11-7-6-8-12-21)31-28(35)30(22,25)24(37-20(4)32)14-15-29(5,36)27(17)34/h6-9,11-15,17-18,22-26,33,36H,3,10,16H2,1-2,4-5H3,(H,31,35)/b13-9+,15-14+/t17-,18+,22-,23-,24+,25-,26+,29+,30+/m0/s1

InChI key

SDZRWUKZFQQKKV-JHADDHBZSA-N

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Categorías relacionadas

Aplicación

Cytochalasin D are isomeric metabolites of Metarrhizium anisopliae. Cytochalasin D possesses antibiotic and antitumor activity. It also impairs maintenance of long term potentiation (LTP) of actin filaments. It is implicated in promoting conditions favorable for depolymerizing actin.

Acciones bioquímicas o fisiológicas

Cell permeable fungal toxin; potent inhibitor of actin polymerization. Disrupts actin microfilaments and activates the p53-dependent pathways causing arrest of the cell cycle at the G1-S transition. Inhibits smooth muscle contraction. Inhibits insulin-stimulated, but not basal, transport of glucose.
Potent inhibitor of actin polymerization; disrupts actin microfilaments; activates the p53-dependent pathways; inhibits smooth muscle contraction; inhibits insulin-stimulated glucose transport.

Otras notas

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.

Código de clase de almacenamiento

10 - Combustible liquids

WGK

WGK 2

Punto de inflamabilidad F

188.6 °F - closed cup - Solvent

Punto de inflamabilidad C

87 °C - closed cup - Solvent

Equipo de protección personal

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Certificado de Análisis

Introduzca el número de lote para buscar un certificado de análisis (COA).

Certificado de origen

Introduzca el número de lote para buscar un Certificado de origen (COO).

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