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C5157

Sigma-Aldrich

Campesterol

~65%

Sinónimos:

24α-Methyl-5-cholesten-3β-ol, 24(R)-Ergost-5-en-3β-ol

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1 MG
MXP 3,376.00
5 MG
MXP 9,922.00
10 MG
MXP 16,596.00

MXP 3,376.00

Disponible para envío el28 de abril de 2025Detalles

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1 MG
MXP 3,376.00
5 MG
MXP 9,922.00
10 MG
MXP 16,596.00

About This Item

Fórmula empírica (notación de Hill):
C28H48O
Número de CAS:
474-62-4
Peso molecular:
400.68
Beilstein:
3216975
Número CE:
207-484-4
Número MDL:
MFCD00010475
Código UNSPSC:
12352211
ID de la sustancia en PubChem:
24892762
NACRES:
NA.28

MXP 3,376.00

Disponible para envío el28 de abril de 2025Detalles

Solicitar un pedido a granel

origen biológico

Glycine max (soybean)

Nivel de calidad

200

Formulario

powder

concentración

~65%

Condiciones de envío

ambient

temp. de almacenamiento

−20°C

cadena SMILES

[H][C@@]12CC=C3C[C@@H](O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@H](CC[C@@]24[H])[C@H](C)CC[C@H](C)C(C)C

InChI

1S/C28H48O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h9,18-20,22-26,29H,7-8,10-17H2,1-6H3/t19-,20+,22-,23-,24+,25-,26-,27-,28+/m0/s1

Clave InChI

SGNBVLSWZMBQTH-ZRUUVFCLSA-N

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Aplicación

Campesterol was used as standard in GC[1] and HPLC[2] analysis of oil samples from plants.

Acciones bioquímicas o fisiológicas

Campesterol is a phytosterol, primarily found in nuts, fruits, legumes and seeds. Though an analogue of cholesterol, it is poorly absorbed in humans and competitively inhibits the absorption of cholesterol. Campesterol decreases the transcription of genes involved in cholesterol metabolism in hepatocytes and enterocytes and has positive impact in treatment of cardiovascular disease.[3][4]
Plant sterol. May lower absorption of dietary cholesterol.

Calidad

Appears ~98% by HPLC and GC, but has been shown by 13C-NMR to contain ~35% dihydrobrassicasterol (24β-methyl-5-cholesten-3β-ol; 24[S]-ergost-5-en-3β-ol).

Nota de preparación

Campesterol yields clear, colorless to faint yellow solution in chloroform at 20 mg/ml.

Pictogramas

Exclamation mark
GHS07

Palabra de señalización

Warning

Clasificaciones de peligro

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órganos de actuación

Respiratory system

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
0000370711
0000370712
0000367951
0000367950
0000324219

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Sigma-Aldrich

F5379

Fucosterol

Stigmasterol phyproof® Reference Substance

PHL82658

Stigmasterol

β-Sitosterol primary reference standard

02090580

β-Sitosterol

Cycloartenol ≥90% (GC)

Sigma-Aldrich

08172

Cycloartenol

Sigma-Aldrich

Sigma-Aldrich

S462330

STIGMASTANOL

D Lütjohann et al.
Journal of lipid research, 36(8), 1763-1773 (1995-08-01)
Absorption of dietary cholesterol, campesterol, and sitosterol, cholesterol balance, and fecal excretion of plant sterols were determined in three unrelated patients with phytosterolemia and three healthy volunteers during constant intake of cholesterol and plant sterols using accurate gas-liquid chromatography-mass spectrometry
Juan P Barrios-Ramos et al.
Journal of the science of food and agriculture, 92(11), 2349-2357 (2012-03-21)
The effect of functional foods alone or in combination (cocoa + soy + oats + fish oil) on hepatic damage in rats affected with metabolic syndrome was investigated. Rats that were given cocoa showed a decrease in the levels of
Hannu Päivä et al.
Clinical pharmacology and therapeutics, 78(1), 60-68 (2005-07-09)
Myopathy, probably caused by 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibition in skeletal muscle, rarely occurs in patients taking statins. This study was designed to assess the effect of high-dose statin treatment on cholesterol and ubiquinone metabolism and mitochondrial function in human skeletal
Kang Jiang et al.
Journal of the American Society for Mass Spectrometry, 30(9), 1700-1712 (2019-05-22)
Phytosterols and tocopherols are essential for plant biochemistry, and they possess beneficial health effects for humans. Evaluating the tandem mass spectrometric (MS/MS) behavior of phytosterols and tocopherols is needed for the development of a qualitative and quantitative method for these
S H Kasmas et al.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 45(11), 1095-1101 (2012-07-18)
Effective statin therapy is associated with a marked reduction of cardiovascular events. However, the explanation for full benefits obtained for LDL cholesterol targets by combined lipid-lowering therapy is controversial. Our study compared the effects of two equally effective lipid-lowering strategies
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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

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    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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