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C5360

SAFC

L-Cysteine

Sinónimos:
(R)-2-Amino-3-mercaptopropionic acid
Fórmula lineal:
HSCH2CH(NH2)CO2H
Número de CAS:
Peso molecular:
121.16
Beilstein:
1721408
Número de EC:
Número MDL:
eCl@ss:
32160406
ID de la sustancia en PubChem:
NACRES:
NA.26

origen biológico

non-animal source

formulario

crystalline powder

manufacturer/tradename

Ajinomoto

technique(s)

cell culture | mammalian: suitable

impurezas

endotoxin, heavy metals, trace metals, tested

mp

240 °C (dec.) (lit.)

solubilidad

H2O: 25 mg/mL

idoneidad

suitable for manufacturing use

actividad extraña

cytotoxicity, tested

SMILES string

N[C@@H](CS)C(O)=O

InChI

1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m0/s1

InChI key

XUJNEKJLAYXESH-REOHCLBHSA-N

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Descripción general

To request documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to the documentation for this product requires a confidentiality disclosure agreement.

Aplicación

L-Cysteine is a non-essential amino acid. It is commonly used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies.

Acciones bioquímicas o fisiológicas

NMDA glutamatergic receptor agonist.

Código de clase de almacenamiento

13 - Non Combustible Solids

WGK

WGK 1

Equipo de protección personal

dust mask type N95 (US), Eyeshields, Gloves

Certificado de Análisis

Certificado de origen

Eun Young Park et al.
Journal of agricultural and food chemistry, 62(26), 6183-6189 (2014-06-01)
The present study examined the impact of the supplementation of glutathione (GSH), γ-L-glutamyl-L-cysteinyl-glycine, on human blood GSH levels. Healthy human volunteers were orally supplemented with GSH (50 mg/kg body weight). Venous blood was collected from the cubital vein before and
Nicholas Kwiatkowski et al.
Nature, 511(7511), 616-620 (2014-07-22)
Tumour oncogenes include transcription factors that co-opt the general transcriptional machinery to sustain the oncogenic state, but direct pharmacological inhibition of transcription factors has so far proven difficult. However, the transcriptional machinery contains various enzymatic cofactors that can be targeted
Takeshi Annoura et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 28(5), 2158-2170 (2014-02-11)
The 10 Plasmodium 6-Cys proteins have critical roles throughout parasite development and are targets for antimalaria vaccination strategies. We analyzed the conserved 6-cysteine domain of this family and show that only the last 4 positionally conserved cysteine residues are diagnostic
Jean-Paul Motta et al.
Inflammatory bowel diseases, 21(5), 1006-1017 (2015-03-05)
Microbiota dysbiosis and impaired barrier function are among the most prominent features of inflammatory bowel disease. In the gastrointestinal tract, hydrogen sulfide (H(2)S) is an important regulator of mucosal homeostasis. We hypothesized that H(2)S promotes resolution of colonic inflammation through
Timothy R Sampson et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(30), 11163-11168 (2014-07-16)
Clustered, regularly interspaced, short palindromic repeats-CRISPR associated (CRISPR-Cas) systems defend bacteria against foreign nucleic acids, such as during bacteriophage infection and transformation, processes which cause envelope stress. It is unclear if these machineries enhance membrane integrity to combat this stress.

Artículos

Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

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