Merck
All Photos(2)

C6012

Sigma-Aldrich

Colesta-3,5-dieno

≥93% (HPLC)

Synonym(s):
Δ3,5-Cholestadiene, Cholesterilene
Empirical Formula (Hill Notation):
C27H44
CAS Number:
Molecular Weight:
368.64
Número de EC:
Número MDL:
ID de la sustancia en PubChem:
NACRES:
NA.77

origen biológico

natural (organic)

Análisis

≥93% (HPLC)

formulario

powder

mp

78-80 °C (lit.)

enviado en

ambient

temp. de almacenamiento

−20°C

SMILES string

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C=CCC[C@]4(C)[C@H]3CC[C@]12C

InChI

1S/C27H44/c1-19(2)9-8-10-20(3)23-14-15-24-22-13-12-21-11-6-7-17-26(21,4)25(22)16-18-27(23,24)5/h6,11-12,19-20,22-25H,7-10,13-18H2,1-5H3/t20-,22+,23-,24+,25+,26+,27-/m1/s1

InChI key

RLHIRZFWJBOHHD-HKQCOZBKSA-N

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Cholesta-3,5-diene ≥93% (HPLC)

Sigma-Aldrich

C6012

Cholesta-3,5-diene

5-α-Cholestane ≥97.0% (HPLC)

Sigma-Aldrich

C8003

5-α-Cholestane

Cholecalciferol ≥98% (HPLC)

Sigma-Aldrich

C9756

Cholecalciferol

Cholesteryl erucate ≥95%

Sigma-Aldrich

C7259

Cholesteryl erucate

biological source

natural (organic)

biological source

-

biological source

synthetic (organic)

biological source

-

assay

≥93% (HPLC)

assay

≥97.0% (HPLC)

assay

≥98% (HPLC)

assay

≥95%

form

powder

form

powder

form

powder

form

powder

mp

78-80 °C (lit.)

mp

80-82 °C (lit.)

mp

83-86 °C (lit.)

mp

-

shipped in

ambient

shipped in

-

shipped in

-

shipped in

-

storage temp.

−20°C

storage temp.

-

storage temp.

2-8°C

storage temp.

−20°C

Aplicación

El colesta-3,5-dieno se utilizó como patrón en la HPLC en los análisis de calidad de diferentes tipos de aceites de oliva y de grasas comestibles.

Acciones bioquímicas o fisiológicas

El colesta-3,5-dieno es un oxisterol, un derivado del colesterol por autooxidación. Los oxisteroles son reguladores no genómicos de la homeostasis del colesterol. Sus efectos biológicos son la prenilación de proteínas, la apoptosis, la modulación del metabolismo de esfingolípidos y la agregación plaquetaria. Los oxisteroles se unen a los receptores hepáticos X, modulan el flujo de salida del colesterol y disminuyen la captación de colesterol por las células.

Nota de preparación

El colesta-3,5-dieno produce una disolución transparente e incolora en cloroformo a 50 mg/ml.

pictogramas

Exclamation mark

Palabra de señalización

Warning

Frases de peligro

Clasificaciones de peligro

Acute Tox. 4 Oral

Código de clase de almacenamiento

11 - Combustible Solids

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Equipo de protección personal

dust mask type N95 (US), Eyeshields, Gloves


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