D8821

Sigma-Aldrich

Dextran from Leuconostoc mesenteroides

average mol wt 60,000-76,000

Fórmula lineal:
(C6H10O5)n
Número de CAS:
EC Number:
MDL number:
NACRES:
NA.25

Quality Level

biological source

bacterial (Leuconostoc mesenteroides)

form

powder

optical activity

[α]20/D 190 to 201 °, c = 2% (w/v) in water

mol wt

average mol wt 60,000-76,000

storage temp.

2-8°C

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Packaging

10, 50, 100, 500 g in poly bottle

Application

Use of dextrans as long and hydrophilic spacer arms improves the performance of immobilized proteins acting on macromolecules.

Biochem/physiol Actions

Dextran is a branched glucan composed of linear a(1→6) linked glucose units and a (1→3) link initiated branches. Dextran ranges in size from 10,000 to 150,000 Kd. Dextrans are used in many applications as volume extenders, stabilizers, matrix components, binding platforms, lubricants and physical structure components.

storage_class_code

11 - Combustible Solids

WGK Germany

WGK 2

Certificado de Análisis

Certificado de origen

Carlos Tassa et al.
Accounts of chemical research, 44(10), 842-852 (2011-06-15)
Advances in our understanding of the genetic basis of disease susceptibility coupled with prominent successes for molecular targeted therapies have resulted in an emerging strategy of personalized medicine. This approach envisions risk stratification and therapeutic selection based on an individual's...
Daniele Venturoli et al.
American journal of physiology. Renal physiology, 288(4), F605-F613 (2005-03-09)
Polydisperse mixtures of dextran or Ficoll have been frequently used as molecular probes for studies of glomerular permselectivity because they are largely inert and not processed (reabsorbed) by the proximal tubules. However, dextrans are linear, flexible molecules, which apparently are...
Dextran 40 therapy made safer by pretreatment with dextran 1.
Karl-Gösta Ljungström
Plastic and reconstructive surgery, 120(1), 337-340 (2007-06-19)
Zhiyang Li et al.
Journal of biomedical nanotechnology, 9(11), 1945-1949 (2013-09-26)
For reducing the steric hindrance and nonspecific binding of the target DNA, the dextran was used as molecular arms to be immobilized on the surface of magnetic nanoparticles (MNPs). Magnetic separation was used in preparation of dextran-MNPs (DMNPs). Aspartic acid...
Yang Yang et al.
Biochimica et biophysica acta, 1840(1), 288-293 (2013-10-01)
Abnormal adhesion of red blood cells (RBCs) to vascular endothelium is often associated with reduced levels of sialic acids on RBC membranes and with elevated levels of pro-adhesive plasma proteins. However, the synergistic effects of these two factors on the...

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