Merck
All Photos(4)

G1279

Sigma-Aldrich

G 418 disulfate salt

suitable for plant cell culture, BioReagent

Synonym(s):
Antibiotic G418
Empirical Formula (Hill Notation):
C20H40N4O10 · 2H2SO4
CAS Number:
Molecular Weight:
692.71
Número MDL:
ID de la sustancia en PubChem:
NACRES:
NA.72

Nivel de calidad

200

línea de producto

BioReagent

formulario

powder

potencia

≥720 μg per mg (Dried basis)

technique(s)

cell culture | plant: suitable

color

white to off-white

solubilidad

100 mg/mL (H2O clear)

espectro de actividad antibiótica

Gram-negative bacteria

application(s)

agriculture

Modo de acción

protein synthesis | interferes

temp. de almacenamiento

2-8°C

SMILES string

OS(O)(=O)=O.OS(O)(=O)=O.CN[C@H]1[C@H](O)[C@@H](OC[C@@]1(C)O)O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H]([C@H](C)O)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O

InChI

1S/C20H40N4O10.2H2O4S/c1-6(25)14-11(27)10(26)9(23)18(32-14)33-15-7(21)4-8(22)16(12(15)28)34-19-13(29)17(24-3)20(2,30)5-31-19;2*1-5(2,3)4/h6-19,24-30H,4-5,21-23H2,1-3H3;2*(H2,1,2,3,4)/t6?,7-,8+,9+,10+,11-,12-,13-,14+,15+,16-,17-,18+,19-,20+;;/m0../s1

InChI key

UHEPSJJJMTWUCP-NKCAIAFTSA-N

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Descripción general

Chemical structure: aminoglycoside

Envase

250 mg in glass bottle
1, 5 g in glass bottle

Aplicación

G418 disulfate salt is an aminoglycoside antibiotic similar in structure to gentamicin used for selection and maintenance of prokaryotic and eukaryotic cells transfected with a iNOS promoter construct and neomycin resistance gene†. Optimal concentrations for selection and maintenance vary by cell lines. Bacteria and algae require 5 μg/mL or less while animal cells may require 300-500 μg/mL.

Precaución

The product is stable for three years when stored at 2-8°C.

Nota de preparación

G418 powder is soluble in water at 100 mg/mL.

pictogramas

Health hazard

Palabra de señalización

Danger

Frases de peligro

Clasificaciones de peligro

Resp. Sens. 1 - Skin Sens. 1

Código de clase de almacenamiento

11 - Combustible Solids

WGK

WGK 3

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

Certificate of Analysis

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Certificate of Origin

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