Merck
  • G2879
All Photos(4)

G2879

Sigma-Aldrich

Glycine hydrochloride

≥99% (HPLC)

Synonym(s):
Aminoacetic acid, Aminoethanoic acid, Glycocoll
Linear Formula:
H2NCH2CO2H · HCl
CAS Number:
Molecular Weight:
111.53
Número de EC:
Número MDL:
eCl@ss:
32160406
ID de la sustancia en PubChem:
NACRES:
NA.32

Nivel de calidad

ensayo

≥99% (HPLC)

mp

176-180 °C (lit.)

SMILES string

Cl.NCC(O)=O

InChI

1S/C2H5NO2.ClH/c3-1-2(4)5;/h1,3H2,(H,4,5);1H

InChI key

IVLXQGJVBGMLRR-UHFFFAOYSA-N

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Descripción general

Research area: Neuroscience

Aplicación

Glycine hydrochloride has been used as a component of Ag (silver)-stripping buffer for multiplex immunohistochemistry in mice tissues.
Glycine hydrochloride has been used:
  • in the preparation of glycine-HCl buffer
  • to elute serum immunoglobulins (IgGs) from the beads in order to check for the complete enrichment of core- and site-specific antibodies
  • to regenerate the sensor to elute the bound C-reactive protein (CRP)

Envase

100, 500 g in poly bottle
1 kg in poly bottle

Acciones bioquímicas o fisiológicas

Glycine acts on receptors which bring out an enhanced chloride conductance. It shows highest concentrations in the spinal cord as compared to elsewhere in the brain. However, it interacts with and allostericaly activates the excitatory receptor N-methyl-D-aspartate (NMDA), thus, resulting in excitatory transmission in brain.
Glycine comprises a single carbon molecule, that is attached to the amino and a carboxyl group. Glycine hydrochloride (Gly·HCl) is capable of liquifying native chitosan and also helps in the preparation of regenerated chitosan membrane. It can serve as an osmoprotectant. Glycine can act as a flexible link in proteins and can also allow the formation of helices. Free glycine may have a protecting role in tissues against ischemia, hypoxia, and reperfusion.Glycine has been studied as a potential treatment for sepsis, arthritis, adult respiratory distress syndrome, and other inflammatory diseases.
Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

pictogramas

Corrosion

Palabra de señalización

Danger

Frases de peligro

Clasificaciones de peligro

Eye Dam. 1 - Skin Corr. 1B

Código de clase de almacenamiento

8A - Combustible, corrosive hazardous materials

WGK

WGK 1

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

Certificate of Analysis

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Certificate of Origin

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