Merck

G5262

Supelco

GAPDH

standard for protein electrophoresis

Sinónimos:
Glyceraldehyde-3-phosphate Dehydrogenase from rabbit muscle, D-Glyceraldehyde 3-phosphate:NAD+ oxidoreductase (phosphorylating), GAPDH
Número de CAS:
Comisión internacional de enzimas:
Número de EC:
Número MDL:

grado

for molecular biology

Nivel de calidad

formulario

powder

mol peso

~36 kDa

envase

vial of 5 mg

technique(s)

electrophoresis: suitable

temp. de almacenamiento

2-8°C

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Este artículo
G889811051466001DGTP-RO
Supelco

Supelco

G5262

GAPDH

Glycine suitable for electrophoresis, ≥99%

Sigma-Aldrich

G8898

Glycine

dGTP =98%, solution, 100 mM, suitable for PCR, suitable for DNA sequencing

Roche

11051466001

dGTP

dGTP PCR Grade, sodium salt

Roche

DGTP-RO

dGTP

form

powder

form

powder

form

solution

form

solution

mol wt

~36 kDa

mol wt

-

mol wt

-

mol wt

-

technique(s)

electrophoresis: suitable

technique(s)

electrophoresis: suitable, western blot: suitable

technique(s)

DNA amplification: suitable, DNA sequencing: suitable, DNA synthesis: suitable, PCR: suitable

technique(s)

-

storage temp.

2-8°C

storage temp.

-

storage temp.

−20°C

storage temp.

−20°C

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

100

Descripción general

GAPDH (Glyceraldehyde-3-phosphate dehydrogenase) catalyzes the conversion of glyceraldehyde-3-phosphate into D-glycerate-1,3-bisphosphate as part of the glycolysis pathway. GAPDH has also been found to function in additional cellular process, such as transcription, apoptosis, oxidative stress and ER to Golgi transport.

Aplicación

GAPDH protein is suitable for use as a molecular weight marker and protein standard for molecular biology applications, including western blotting and mass spectometry.

Acciones bioquímicas o fisiológicas

Glyceraldehyde-3-phosphate dehydrogenase catalyzes the conversion of glyceraldehyde-3-phosphate into D-glycerate-1,3-bisphosphate as part of the glycolysis pathway.

Código de clase de almacenamiento

11 - Combustible Solids

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)


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Ejemplo

T1503
Referencia del producto
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25G
Tamaño del envase/cantidad

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705578-5MG-PW

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Ling Ji et al.
Molecular therapy. Nucleic acids, 19, 546-561 (2020-01-14)
Long non-coding RNAs (lncRNAs) are crucial molecules in tumorigenesis and tumor growth in various human cancers, including colorectal cancer (CRC). Studies have revealed that lncRNAs can regulate cellular processes in cancers by interacting with proteins, for example RNA-binding proteins (RBPs).
Craig Nicholls et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(33), 13308-13313 (2012-08-01)
Oxidative stress regulates telomere homeostasis and cellular aging by unclear mechanisms. Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) is a key mediator of many oxidative stress responses, involving GAPDH nuclear translocation and induction of cell death. We report here that GAPDH interacts with
S A Ismail et al.
Acta crystallographica. Section D, Biological crystallography, 61(Pt 11), 1508-1513 (2005-10-22)
The crystal structure of human liver glyceraldehyde-3-phosphate dehydrogenase (GAPDH) has been determined. This structure represents the first moderate-resolution (2.5 A) and crystallographically refined (Rfree = 22.9%) human GAPDH structure. The liver GAPDH structure consists of a homotetramer, each subunit of
Joyce Jing Yi Wong et al.
Proceedings of the National Academy of Sciences of the United States of America, 103(28), 10735-10740 (2006-07-04)
Type I IFNs induce the expression of IFN-stimulated gene 15 (ISG15) and its conjugation to cellular targets. ISGylation is a multistep process involving IFN-inducible Ube1L, UbcH8, and a yet-to-be identified E3 ligase. Here we report the identification of an IFN-induced
A Bosch-Comas et al.
Cellular and molecular life sciences : CMLS, 63(6), 723-734 (2006-02-28)
The biological functions of the more than one hundred genes coding for deubiquitinating enzymes in the human genome remain mostly unknown. The USP25 gene, located at 21q11.2, encodes three protein isoforms produced by alternative splicing. While two of the isoforms

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