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G6019

Sigma-Aldrich

Glyceraldehyde-3-phosphate Dehydrogenase from human erythrocytes

lyophilized powder, 50-150 units/mg protein

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Sinónimos:
D-Glyceraldehyde 3-phosphate:NAD+ oxidoreductase (phosphorylating), GAPDH
Número de CAS:
9001-50-7
Comisión internacional de enzimas:
1.2.1.12 (BRENDA, IUBMB)
Número MDL:
MFCD00131203
NACRES:
NA.54

formulario

lyophilized powder

Nivel de calidad

200

specific activity

50-150 units/mg protein

composición

Protein, 40-70% biuret

Nº de acceso UniProt

P04406

actividad extraña

3-Phosphoglyceric phosphokinase ≤2%

temp. de almacenamiento

−20°C

Gene Information

human ... GAPDH(2597)

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Este artículo
G7882G2267G5885
Sigma-Aldrich

Sigma-Aldrich

G6019

Glyceraldehyde-3-phosphate Dehydrogenase from human erythrocytes

L-Glutamic Dehydrogenase from bovine liver Type III, lyophilized powder, ≥20 units/mg protein

Sigma-Aldrich

G7882

L-Glutamic Dehydrogenase from bovine liver

Glyceraldehyde-3-phosphate Dehydrogenase from rabbit muscle lyophilized powder, ≥75 units/mg protein

Sigma-Aldrich

G2267

Glyceraldehyde-3-phosphate Dehydrogenase from rabbit muscle

Glucose-6-phosphate Dehydrogenase from Leuconostoc mesenteroides lyophilized powder, >= 550 units/mg protein (biuret)

Sigma-Aldrich

G5885

Glucose-6-phosphate Dehydrogenase from Leuconostoc mesenteroides

specific activity

50-150 units/mg protein

specific activity

≥20 units/mg protein

specific activity

≥75 units/mg protein

specific activity

>= 550 units/mg protein (biuret)

UniProt accession no.

P04406

UniProt accession no.

P00366

UniProt accession no.

-

UniProt accession no.

-

foreign activity

3-Phosphoglyceric phosphokinase ≤2%

foreign activity

-

foreign activity

3-Phosphoglyceric phosphokinase ≤0.05%, lactic dehydrogenase, myokinase, and pyruvate kinase ≤0.01%, triosephosphate isomerase ≤0.1%

foreign activity

6-Phosphogluconic dehydrogenase, hexokinase, NADH oxidase and NADPH oxidase ≤0.005%, PGI ≤0.01%

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

300

Acciones bioquímicas o fisiológicas

Glyceraldehyde-3-phosphate dehydrogenase catalyzes the conversion of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate as part of glycolysis. It has also been shown to have roles in initiation of apoptosis, transcription activation and the shuttling of ER to Golgi vesicles<<<18,New>>>.

Definición de unidad

One unit will reduce 1.0 μmole of 3-phosphoglycerate to D-glyceraldehyde 3-phosphate per min in a coupled system with 3-phosphoglyceric phosphokinase at pH 7.6 at 25 °C.

Forma física

Lyophilized powder containing sodium citrate buffer salts

inhibidor

Referencia del producto
Descripción
Precios

Código de clase de almacenamiento

11 - Combustible Solids

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificates of Analysis (COA)

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Las referencias de los producto se combinan con los tamaños de envase y las cantidades cuando se muestran en la página web, por ejemplo: T1503-25G. Asegúrese de introducir el número de producto ÚNICAMENTE en el campo del Número de producto (Ejemplo T1503).

Ejemplo

T1503
Referencia del producto
-
25G
Tamaño del envase/cantidad

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Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

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Pablo Moreno-Acosta et al.
Anticancer research, 32(10), 4319-4325 (2012-10-13)
The aim of this study was to evaluate the predictive utility of Insulin-like growth factor-1 receptor (IGF1R), IGF1, IGF2, Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) and of hemoglobin levels for tumor response to exclusive radiotherapy, in patients with locally advanced Human papillomavirus
Bing Fang et al.
Biochimie, 95(2), 251-257 (2012-09-27)
siRNA is promising in anti-tumor therapy. The main challenge is lack of tumor-specific intracellular delivery. In this study, a 6 amino acids peptide (A1) with high affinity for vascular endothelial growth factor receptor-1 (VEGFR1) was conjugated with a cell penetrating
Yuki Ikeda et al.
Archives of biochemistry and biophysics, 528(2), 141-147 (2012-09-25)
Cyclooxygenase (COX)-2 is an inducible inflammatory protein whose expression is partially regulated at the post-transcriptional level. We investigated whether glyceraldehyde-3-phosphate dehydrogenase (GAPDH) binds to the AU-rich element (ARE) of COX-2 mRNA for its degradation. Knockdown of GAPDH in hepa1c1c7 cells
Chiaki Inadomi et al.
Biochemical and biophysical research communications, 425(3), 656-661 (2012-08-01)
There is increasing evidence demonstrating that glutaredoxin 1 (GRX1), a cytosolic enzyme responsible for the catalysis of protein deglutathionylation, plays distinct roles in inflammation and apoptosis by inducing changes in the cellular redox system. In this study, we investigated whether
Irina A Sevostyanova et al.
Biochemical and biophysical research communications, 427(3), 649-653 (2012-10-03)
Sperm-specific glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDS) is normally expressed only in sperms, but not in somatic tissues. Analysis of the expression of GAPDS mRNA in different cancer cell lines shows that the content of GAPDS mRNA is enhanced in some
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