All Photos(8)
G7017
β-Glucuronidase from Helix pomatia
Type HP-2, aqueous solution, ≥100,000 units/mL
All Photos(8)
Synonym(s):
β-D-Glucuronide glucuronosohydrolase
CAS Number:
Número MDL:
NACRES:
NA.54
Recommended Products
origen biológico
Helix pomatia
Nivel de calidad
tpo
Type HP-2
formulario
aqueous solution
specific activity
≥100,000 units/mL
secondary activity
≤7,500 units/mL sulfatase
enviado en
wet ice
temp. de almacenamiento
2-8°C
Looking for similar products? Visit Product Comparison Guide
Related Categories
Descripción general
β-Glucuronidase Type H-2 from Helix pomatia is a crude solution of enzymes derived from the digestive juices of the Roman snail. β-glucuronidases derived from mollusks often contain sulfatase activity. Both activities are useful in the hydrolysis of metabolites for toxicology and biomarker analysis. For a broader look at our β-Glucuronidase product line and their uses see our page about Drug Metabolite Analysis
Aplicación
- Sample preparation for LC/MS through digestion of glucuronide conjugated compounds for biomarker and toxicology research.
- Removal of glucuronide conjugates such as for the preparation of Baicalein.
New Technical Article Comparing Performance of Different Enzymes
Learn more
about recent application data generated by Sigma R&D to optimize hydrolysis for different drug classes using enzymes from different sources and the use of a chromatographicaly purified enzyme to reduce the effect of esterase activity resulting in conversion of 6-MAM to Morphine
Learn more
about recent application data generated by Sigma R&D to optimize hydrolysis for different drug classes using enzymes from different sources and the use of a chromatographicaly purified enzyme to reduce the effect of esterase activity resulting in conversion of 6-MAM to Morphine
Envase
1, 2, 5, 10, 25, 100 mL
Acciones bioquímicas o fisiológicas
Endogenous beta-glucuronidase is a lysosomal enzyme involved in digestion of glucuronide-modified catabolites.
Microbial beta-glucuronidase found in microbiota can cause re-absorption of metabolites by hydrolysis of glucuronide conjugates of xenobiotic and endobiotic metabolites.
Microbial beta-glucuronidase found in microbiota can cause re-absorption of metabolites by hydrolysis of glucuronide conjugates of xenobiotic and endobiotic metabolites.
Used for the hydrolysis of glucuronide conjugates in urinary metabolite analysis
Características y beneficios
- pH optima 4.0 - 5.0.
- Sulfatase pH optima 6.2
- Low Sulfatase activity (<7,500 units/mL).
- Ammonium Sulfate suspension.
- Mollusk-derived beta-glucuronidase.
- Useful for acidic hydrolysis of glucuronides in low pH samples.
Calidad
Many β-glucuronidases derived from mollusks also contain sulfatase activity.
Ligadura / enlace
Similar to G0876, but produced by Sigma.
Definición de unidad
One Sigma or modified Fishman unit will liberate 1.0 μg of phenolphthalein from phenolphthalein glucuronide per hr at 37 °C at pH 5.0 (30 min assay).
Sulfatase Unit Definition: One unit of sulfatase will hydrolyze 1.0 μmole p-nitrocatechol sulfate per hr at pH 5.0 at 37 °C.
Forma física
Aqueous solution in ~1.0 M ammonium sulfate with 3 mM sodium azide as preservative.
Palabra de señalización
Danger
Frases de peligro
Consejos de prudencia
Clasificaciones de peligro
Resp. Sens. 1 - Skin Sens. 1
Código de clase de almacenamiento
10 - Combustible liquids
WGK
WGK 3
Certificate of Analysis
Enter Lot Number to search for Certificate of Analysis (COA).
Certificate of Origin
Enter Lot Number to search for Certificate of Origin (COO).
Data Sheets
More Documents
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service