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G7403

Glicina

Name: Glicina
Brand: SIGMA

≥99% (titration), suitable for electron microscopy, BioXtra

Sinónimos:

Glicocola, Ácido aminoacético, Ácido aminoetanoico

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Fórmula lineal:

NH₂CH₂COOH

Número CAS:

56-40-6

Peso molecular:

75.07

NACRES:

NA.26

PubChem Substance ID:

24895306

eCl@ss:

32160406

UNSPSC Code:

12352209

EC Number:

200-272-2

MDL number:

MFCD00008131

Beilstein/REAXYS Number:

635782

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Propiedades

Nombre del producto

Glicina, BioXtra, ≥99% (titration)

product line

BioXtra

Quality Segment

200

assay

≥99% (titration)

form

powder

technique(s)

electron microscopy: suitable

impurities

Insoluble matter, passes filter test

ign. residue

≤0.05%

loss

≤0.05% loss on drying, HV, 20-26 °C

color

white

pKa (25 °C)

(1) 2.35, (2) 9.60, 2.35

mp

240 °C (dec.) (lit.)

solubility

1 M HCl: 1 M, clear, colorless

anion traces

chloride (Cl^-): ≤0.005%, sulfate (SO₄^2-): ≤0.005%

cation traces

Al: ≤0.0005%, As: ≤0.00001%, Ba: ≤0.0005%, Bi: ≤0.0005%, Ca: ≤0.001%, Cd: ≤0.0005%, Co: ≤0.0005%, Cr: ≤0.0005%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.005%, Li: ≤0.0005%, Mg: ≤0.0005%, Mn: ≤0.0005%, Mo: ≤0.0005%, NH₄⁺: ≤0.02%, Na: ≤0.02%, Ni: ≤0.0005%, Pb: ≤0.0005%, Sr: ≤0.0005%, Zn: ≤0.0005%

absorption

≤0.04 at 260 in 1 M HCl at 1 M, ≤0.04 at 280 in 1 M HCl at 1 M

SMILES string

NCC(O)=O

UV absorption

λ: 260 nm A_max: ≤0.04, λ: 260 nm A_max: 0.003, λ: 260 nm A_max: 0.006

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChI key

DHMQDGOQFOQNFH-UHFFFAOYSA-N

Gene Information

rat ... Grin2a(24409)

Descripción

Application

Glycine has been used to quench unreacted aldehyde during sample (nuclei) preparation for scanning electron microscope. It has also been used for sample fixation in the process of immunolabeling.

Biochem/physiol Actions

Glycine is a non-essential amino acid. Influx of calcium through the cell membrane is mediated by glycine-gated channel. Glycine participates in the synthesis of porphyrins, purine and serine. It also serves as a competitive agonist for glutamate in binding to the NMDA (N-methyl-D-aspartate) receptors. Glycine synthesis might be increased in rapidly proliferating cancer cells, due to increased demand for the amino acid.

Neurotransmisor inhibidor de la médula espinal, regulador alostérico de los receptores NMDA.

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

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Este artículo	G7126	15527	G8790
Sigma-Aldrich G7403 Glicina	Sigma-Aldrich G7126 Glicina	Sigma-Aldrich 15527 Glicina	Sigma-Aldrich G8790 Glicina
description BioXtra, ≥99% (titration)	description ReagentPlus^®, ≥99% (HPLC)	description meets analytical specification of Ph. Eur., BP, USP, 99-101% (based on anhydrous substance)	description from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, ≥98.5%
form powder	form powder	form crystalline powder	form powder
technique(s) electron microscopy: suitable	technique(s) western blot: suitable	technique(s) IR spectroscopy: suitable	technique(s) cell culture \| mammalian: suitable
assay ≥99% (titration)	assay ≥99% (HPLC)	assay 99-101% (based on anhydrous substance)	assay ≥98.5%
product line BioXtra	product line ReagentPlus^®	product line -	product line -
mp 240 °C (dec.) (lit.)	mp 240 °C (dec.) (lit.)	mp 240 °C (dec.) (lit.)	mp 240 °C (dec.) (lit.)
impurities Insoluble matter, passes filter test	impurities ≤0.01% Ammonia	impurities hydrolyzable substances, complies, organic volatile impurities, complies (GC), residual solvents, complies, ≤0.001% heavy metals (as Pb), ≤1.0% ninhydrin-positive substances	impurities endotoxin, tested

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Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c