G8898

Glycine

suitable for electrophoresis, ≥99%

• Synonym(s): Aminoacetic acid, Aminoethanoic acid, Glycocoll
• Linear Formula: NH₂CH₂COOH
• CAS Number: 56-40-6
• Molecular Weight: 75.07
• Beilstein: 635782
• Número de EC: 200-272-2
• Número MDL: MFCD00008131
• eCl@ss: 32160406
• ID de la sustancia en PubChem: 24895355

Properties

• Nivel de calidad: 200
• ensayo: ≥99%
• formulario: powder
• technique(s): electrophoresis: suitable; western blot: suitable
• impurezas: ≤0.01% Insoluble matter
• color: white to off-white
• pKa (25 °C): (1) 2.35, (2) 9.60; 2.35
• mp: 240 °C (dec.) (lit.)
• solubilidad: H₂O: 200 mg/mL, clear, colorless to faintly yellow
• trazas de anión: chloride (Cl^-): ≤70 ppm
• trazas de catión: heavy metals (as Pb): ≤20 ppm
• absorción: ≤0.15 at 280 at 1 M
• SMILES string: NCC(O)=O
• InChI: 1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
• InChI key: DHMQDGOQFOQNFH-UHFFFAOYSA-N
• Gene Information: rat ... Grin2a(24409)

Description

Descripción general

Glycine is a molecule with pI of 6.7, which is similar to the pH of stacking gel. It has advantage of low mobility, hydrophobicity and it does not associate with proteins. Glycine is a component of Tris-glycine and Tris-glycine-SDS (sodium dodecyl sulfate) running buffers for polyacrylamide gel electrophoresis. Glycine is also a component of Towbin′s transfer buffer for Western blots.

Aplicación

• Glycine has been used for the preparation of gelatin composites scaffold.
• It has been used in the elution buffer to extract protein using HiTrap protein G column.
• It has been used in the SDS-sample, running and transfer buffers prepared for SDS-PAGE (sodium dodecyl sulfate polyacrylamide gel electrophoresis) and western blotting.

Acciones bioquímicas o fisiológicas

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Nota de análisis

Tested for use in electrode buffers for PAGE and in transfer buffers for Western blots.

Safety Information

• Código de clase de almacenamiento: 11 - Combustible Solids
• WGK: WGK 1
• Punto de inflamabilidad F: Not applicable
• Punto de inflamabilidad C: Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)