H3911

L-Histidine

• Synonym(s): (S)-2-Amino-3-(4-imidazolyl)propionic acid, NSC 137773
• Empirical Formula (Hill Notation): C₆H₉N₃O₂
• CAS Number: 71-00-1
• Molecular Weight: 155.15
• Beilstein: 84088
• Número de EC: 200-745-3
• Número MDL: MFCD00064315
• eCl@ss: 32160406
• ID de la sustancia en PubChem: 57654248
• NACRES: NA.26

Properties

• origen biológico: non-animal source
• Nivel de calidad: 400
• ensayo: ≥98.5%
• formulario: crystalline powder
• manufacturer/tradename: Ajinomoto
• technique(s): cell culture | mammalian: suitable
• impurezas: endotoxin, heavy metals, trace metals, residual solvents, tested
• mp: 282 °C (dec.) (lit.)
• solubilidad: H₂O: 50 mg/mL
• idoneidad: suitable for manufacturing use
• application(s): pharmaceutical (small molecule)
• actividad extraña: cytotoxicity, tested
• SMILES string: N[C@@H](Cc1c[nH]cn1)C(O)=O
• InChI: 1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m0/s1
• InChI key: HNDVDQJCIGZPNO-YFKPBYRVSA-N
• Gene Information: human ... CA1(759) , CA2(760)

Description

Descripción general

Our SAFC^® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of downstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

To request documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to the documentation for this product requires a confidentiality disclosure agreement.

Aplicación

L-Histitidine is an essential amino acid. It is used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies.

Acciones bioquímicas o fisiológicas

Precursor of histamine by action of histidine decarboxylase.

Información legal

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Código de clase de almacenamiento: 11 - Combustible Solids
• WGK: WGK 1
• Punto de inflamabilidad F: Not applicable
• Punto de inflamabilidad C: Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)