Merck
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HT5011

Sigma-Aldrich

Formalin solution, neutral buffered, 10%

case of 48 × 15 mL, histological tissue fixative

Número MDL:
ID de la sustancia en PubChem:
NACRES:
NA.47

caducidad

Expiry date on the label.

envase

case of 48 × 15 mL

concentración

10% formalin (approx. 4% formaldehyde)

color

colorless

pH

6.90-7.10

densidad

1.080 g/cm3

application(s)

hematology
histology

temp. de almacenamiento

room temp

InChI

1S/CH2O/c1-2/h1H2

InChI key

WSFSSNUMVMOOMR-UHFFFAOYSA-N

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Descripción general

Formaldehyde is both a non-coagulant and an additive fixative. Formaldehyde is known to penetrate tissue quickly, but the fixation process may take a long time to form the various cross links with tissue proteins. Formalin fixation is thought to form cross links between the aldehydes and the proteins, creating a gel, thus retaining cellular constituents in their in vivo relationship. Once properly fixed, the tissue should be able to withstand the subsequent stages of tissue processing or staining. Although there is no true universal fixative, 10% neutral buffered formalin (NBF) is perhaps the most commonly used fixative throughout the world for light microscopy and is a somewhat forgiving fixative. Of the dozens and dozens of available fixatives, it is hard to imagine a fixative more commonly used than 10% NBF. 10% neutral buffered formalin is well suited for large throughput laboratories, and requires a relatively short period of fixation, but can also be used for the long-term storage of tissue.

Aplicación

10% neutral buffered formalin (NBF) is a popular general purpose histological fixative. It has been used to fix tissues, protein complexes and tumor samples.[1][2][3]
Popular general purpose histological fixative.

Envase

Case containers are polypropylene with white leak-proof lids and are partially prefilled with 10% NBF.

Forma física

Neutral buffered solution

Almacenamiento y estabilidad

Store tightly closed at room temperature. Do not freeze.

pictogramas

Exclamation markHealth hazard

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Muta. 2 - Skin Sens. 1

Código de clase de almacenamiento

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Punto de inflamabilidad F

185.0 °F

Punto de inflamabilidad C

85 °C

Equipo de protección personal

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Certificate of Analysis

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Certificate of Origin

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Product Information Sheet

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