K4639

Sigma-Aldrich

Anti-Potassium Channel Kv1.7 antibody produced in rabbit

affinity isolated antibody, lyophilized powder

Sinónimos:
Anti-KCNA7, Anti-Voltage gated K+ channel KV1.7
MDL number:
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

mouse

should not react with

human

application(s)

western blot: 1:200 using heart membranes

conjugate

unconjugated

UniProt accession no.

storage temp.

−20°C

Gene Information

mouse ... Kcna7(16495)

Immunogen

peptideTTRKAQEIHGKAPG (C) corresponding to residues 2-15 of mouse Kv1.7.

Target description

Kv1.7 voltage-gated K+ channel is a member of the Shaker family of K+ channels that includes eight members (Kv1.1- Kv1.8). The biophysical and pharmacological properties of the Kv1.7 channel closely resemble that of the ultra-rapidly activating delayed rectifier (IKur) in cardiac tissue. This current plays a central role in cardiac atria repolarization that was largely believed to correspond to the activity of the Kv1.5 channel.

Physical form

Lyophilized powder from phosphate buffered saline, pH 7.4, containing 1% BSA and 0.025% sodium azide.

Reconstitution

Reconstitute the lyophilized vial with 50 μL or 200 μL deionized water, depending on package size. Further dilutions should be made using a carrier protein such as BSA (1-3%).
V I Kashuba et al.
Gene, 268(1-2), 115-122 (2001-05-23)
A novel human potassium channel gene was identified and isolated. The maximal open reading frame encodes a protein of 456 amino acids. The predicted product exhibits 91% amino acid identity to the murine voltage-gated potassium channel protein Kv1.7 (Kcna7), which...

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico

Redes sociales

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon

Merck

Investigación. Desarrollo. Producción.

Somos un proveedor líder para la industria de Ciencias de la Vida con soluciones y servicios para investigación, desarrollo y producción biotecnológicos, y para desarrollo y producción de tratamientos farmacéuticos

© 2021 Merck KGaA, Darmstadt, Alemania y/o sus filiales. Todos los derechos reservados.

Queda estrictamente prohibida la reproducción sin permiso de cualquiera de los materiales de la página web.