peptideTTRKAQEIHGKAPG (C) corresponding to residues 2-15 of mouse Kv1.7.
Kv1.7 voltage-gated K+ channel is a member of the Shaker family of K+ channels that includes eight members (Kv1.1- Kv1.8). The biophysical and pharmacological properties of the Kv1.7 channel closely resemble that of the ultra-rapidly activating delayed rectifier (IKur) in cardiac tissue. This current plays a central role in cardiac atria repolarization that was largely believed to correspond to the activity of the Kv1.5 channel.
Lyophilized powder from phosphate buffered saline, pH 7.4, containing 1% BSA and 0.025% sodium azide.
Reconstitute the lyophilized vial with 50 μL or 200 μL deionized water, depending on package size. Further dilutions should be made using a carrier protein such as BSA (1-3%).