Merck
Todas las fotos(2)

L1376

Sigma-Aldrich

Linoleic acid

≥99%

Sinónimos:
Telfairic acid, 9-cis,12-cis-Linoleic acid, cis-9,cis-12-Octadecadienoic acid
Fórmula lineal:
CH3(CH2)4CH=CHCH2CH=CH(CH2)7CO2H
Número de CAS:
Peso molecular:
280.45
Beilstein:
1727101
Número de EC:
Número MDL:
ID de la sustancia en PubChem:

Nivel de calidad

200

origen biológico

plant oil (safflower)

ensayo

≥99%

formulario

liquid

índice de refracción

n20/D 1.466 (lit.)

bp

229-230 °C/16 mmHg (lit.)

mp

−5 °C (lit.)

densidad

0.902 g/mL at 25 °C (lit.)

grupo funcional

carboxylic acid

enviado en

ambient

temp. de almacenamiento

−20°C

SMILES string

OC(CCCCCCC/C=C\C/C=C\CCCCC)=O

InChI

1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20)/b7-6-,10-9-

InChI key

OYHQOLUKZRVURQ-HZJYTTRNSA-N

Gene Information

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Envase

1, 5, 10, 25 g in ampule
10, 500 mg in ampule

Acciones bioquímicas o fisiológicas

Linoleic acid is an n-6 polyunsaturated essential fatty acid (PUFA) used as a precursor of arachidonic acid (AA) and various prostaglandins. Linoleic acid may be used to improve the delivery and efficacy of anticancer drugs and in cancer protection.
Linoleic acid increases cell proliferation and gene expression of PPARα and its target genes such as acyl-CoA oxidase in primary duck hepatocytes .

Código de clase de almacenamiento

10 - Combustible liquids

WGK

WGK 1

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Equipo de protección personal

Eyeshields, Gloves

Certificado de Análisis

Introduzca el número de lote para buscar un certificado de análisis (COA).

Certificado de origen

Introduzca el número de lote para buscar un Certificado de origen (COO).

Céline Robo et al.
Acta biomaterialia, 72, 362-370 (2018-03-22)
Poly(methyl methacrylate) (PMMA) is the most commonly used material for the treatment of osteoporosis-induced vertebral compression fractures. However, its high stiffness may introduce an increased risk of adjacent vertebral fractures post-surgery. One alternative in overcoming this concern is the use
Philong Ta et al.
Journal of bacteriology, 193(8), 1981-1990 (2011-02-22)
The mshA::Tn5 mutant of Mycobacterium smegmatis does not produce mycothiol (MSH) and was found to markedly overproduce both ergothioneine and an ~15-kDa protein determined to be organic hydroperoxide resistance protein (Ohr). An mshA(G32D) mutant lacking MSH overproduced ergothioneine but not
James E Dombrowski et al.
BMC research notes, 7, 807-807 (2014-11-19)
Previously it has been shown that mechanical wounding, salinity and heat activated a 46 kDa and 44 kDa mitogen-activated protein kinases (MAPKs) in forage related grasses. Forage and turf related grasses are utilized in diverse environments where they are routinely subjected to
Allison Dilzer et al.
Critical reviews in food science and nutrition, 52(6), 488-513 (2012-03-29)
Conjugated linoleic acid (CLA) has drawn significant attention in the last two decades for its variety of biologically beneficial effects. CLA reduces body fat, cardiovascular diseases and cancer, and modulates immune and inflammatory responses as well as improves bone mass.
Laurent L'homme et al.
Journal of lipid research, 54(11), 2998-3008 (2013-09-06)
The NLRP3 inflammasome is involved in many obesity-associated diseases, such as type 2 diabetes, atherosclerosis, and gouty arthritis, through its ability to induce interleukin (IL)-1β release. The molecular link between obesity and inflammasome activation is still unclear, but free fatty

Artículos

Linoleic acid in Cell Culture

Importance and uses of linoleic acid in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures

Omega-3 Fatty Acids and Heart Disease

The potential for the prevention and treatment of cardiovascular disease through increased dietary intake of omega-3 (w-3) fish oils is not a recent scientific discovery.

Protocolos

LPL Activity Assay Protocol

Lipoprotein lipase (LPL) hydrolyzes triglycerides associated with VLDL.

HPLC Analysis of Free Fatty Acids on SUPELCOSIL™ LC-8

Separation of Palmitic acid; Linoleic acid; Palmitelaidic acid; Linolelaidic acid; Stearic acid; Oleic acid; Elaidic acid; Methyl palmitoleate.

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