Merck
  • L5768
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L5768

Sigma-Aldrich

Lanosterol

≥93%, powder

Synonym(s):
3β-Hydroxy-8,24-lanostadiene, 8,24-Lanostadien-3β-ol
Empirical Formula (Hill Notation):
C30H50O
CAS Number:
Molecular Weight:
426.72
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.77

Quality Level

Assay

≥93%

form

powder

color

white to off-white

storage temp.

−20°C

SMILES string

[H][C@@]1(CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](O)C(C)(C)[C@]4([H])CC3)[C@H](C)CC\C=C(/C)C

InChI

1S/C30H50O/c1-20(2)10-9-11-21(3)22-14-18-30(8)24-12-13-25-27(4,5)26(31)16-17-28(25,6)23(24)15-19-29(22,30)7/h10,21-22,25-26,31H,9,11-19H2,1-8H3/t21-,22-,25+,26+,28-,29-,30+/m1/s1

InChI key

CAHGCLMLTWQZNJ-BQNIITSRSA-N

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This Item
700063P700099P700073P
Lanosterol ≥93%, powder

Sigma-Aldrich

L5768

Lanosterol

lanosterol 8,24-lanostadien-3β-ol, powder

Avanti

700063P

lanosterol

lanosterol-95 8,24-lanostadien-3β-ol, powder

Avanti

700099P

lanosterol-95

14-demethyl-lanosterol 4,4-dimethyl-cholest-8(9),24-dien-3β-ol, powder

Avanti

700073P

14-demethyl-lanosterol

assay

≥93%

assay

>99% (TLC)

assay

>95% (TLC)

assay

>99% (TLC)

form

powder

form

powder

form

powder

form

powder

color

white to off-white

color

-

color

-

color

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−70°C

Quality Level

200

Quality Level

-

Quality Level

-

Quality Level

-

General description

Lanosterol, an amphipathic molecule, that is produced by lanosterol synthase (LSS). It is enriched in the lens.

Application

Lanosterol has been used:
  • as a standard in HPLC for the quantification in testis samples
  • in S-adenosyl-L-methionine:Δ24-sterol-C-methyltransferase (SMT) assay
  • to treat wild-type cells growing in rich medium to know its effects on Sre1 protein

Biochem/physiol Actions

Cholesterol precursor sterol.
Lanosterol serves as an endogenous selective modulator of macrophage immunity.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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