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M7273

Sigma-Aldrich

Anti-Microtubule-Associated Proteins (MAPs) antibody produced in rabbit

whole antiserum

Número MDL:

origen biológico

rabbit

Nivel de calidad

200

conjugado

unconjugated

forma del anticuerpo

whole antiserum

antibody product type

primary antibodies

clon

polyclonal

contiene

15 mM sodium azide

species reactivity

mammals

technique(s)

western blot: 1:200

Nº de acceso UniProt

enviado en

dry ice

temp. de almacenamiento

−20°C

Gene Information

Descripción general

Microtubule-associated protein 2 (MAP2) is a neuronal protein. It belongs to the MAP2/Tau family. This gene is located to human chromosome 2q34-q35. MAP2 is present in neurons. MAP2 is the major microtubule-associated protein of brain tissue. There are two major classes of heat stable MAPs; two are similarly sized with apparent molecular weights of 280kDa (MAP2a and MAP2b) and the third with a lower molecular weight of 70kDa (MAP2c).

Especificidad

Reacts with the two major classes of heat stable MAPs (MAP2 and τ). Does not react with MAP1 or tubulin.

Inmunógeno

heat stable MAPs prepared from bovine brain.

Aplicación

Anti-Microtubule-Associated Proteins (MAPs) antibody produced in rabbit has been used in:
  • immunofluorescent labelling
  • immunohistochemistry
  • immunoprecipitation
  • immunofluorescence staining
  • western blotting

Acciones bioquímicas o fisiológicas

Microtubule-associated protein 2 (MAP2) interacts with microtubules to maintain the structure of dendrites. It plays a major role in supporting the actin cytoskeleton in spines, binding and nucleating filamentous actin (f-actin) to modulate spine morphology. Microtubules function as structural and mobility elements in mitosis, intracellular transport, flagellar movement and in the cytoskeleton.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Código de clase de almacenamiento

12 - Non Combustible Liquids

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificate of Analysis

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Certificate of Origin

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SDS

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