Merck
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PLA0013

Sigma-Aldrich

Rabbit anti-ROCK2 Antibody, Affinity Purified

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Synonym(s):
ROCK-II, Rho kinase 2, Rho-associated, coiled-coil-containing protein kinase 2, coiled-coil-containing protein kinase II, p164 ROCK-2, rho-associated
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

100

forma del anticuerpo

affinity purified immunoglobulin

antibody product type

primary antibodies

grado

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species reactivity

human

technique(s)

immunoprecipitation (IP): 2-5 μg/mg
western blot: 1:10,000-1:25,000

nº de acceso

NP_004841.1

Nº de acceso UniProt

enviado en

wet ice

temp. de almacenamiento

2-8°C

Gene Information

rabbit ... ROCK2(9475)

Inmunógeno

The epitope recognized by PLA0013 maps to a region between residues 1320 and the C-terminus (residues 1388) of human ROCK2 using the number given in entry NP_004841.1 (GeneID 9475)

Forma física

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide

Otras notas

Rho-associated protein kinase 2 (ROCK2), or Rho kinase alpha, is a serine-threonine protein kinase that plays an important role in cellular apoptosis, growth, cell motility and cell contraction. ROCK2 shares an overall 65% homology in amino acid sequence with ROCK1. The ROCK1 and ROCK2 isoforms are products of two separate genes. Both ROCK1 and ROCK2 are downstream targets of the Rho A small GTP-binding protein. As downstream effectors of RhoA, ROCK1 and ROCK2 mediate changes in the actin cytoskeleton via phosphorylation of target proteins such as the MBS subunit of MLCP, MLC, ERM proteins, protein LIM kinase and adducin.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Código de clase de almacenamiento

12 - Non Combustible Liquids

WGK

nwg

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

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