Merck
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PZ0015

Sigma-Aldrich

Trovafloxacin mesylate

>98% (HPLC)

Synonym(s):
(1α,5α,6α)-7-(6-Amino-3-azabicyclo[3.1.0]hex-3-yl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid methanesulfonate, CP-99219-27, Trovafloxacin methanesulfonate
Empirical Formula (Hill Notation):
C20H15F3N4O3 · CH3SO3H
CAS Number:
Molecular Weight:
512.46
Número MDL:
ID de la sustancia en PubChem:
NACRES:
NA.77

Nivel de calidad

100

ensayo

>98% (HPLC)

formulario

powder

manufacturer/tradename

Pfizer®

color

white to off-white

solubilidad

DMSO: >10 mg/mL

emisor

Pfizer

temp. de almacenamiento

room temp

SMILES string

CS(O)(=O)=O.NC1C2CN(CC12)c3nc4N(C=C(C(O)=O)C(=O)c4cc3F)c5ccc(F)cc5F

InChI

1S/C20H15F3N4O3.CH4O3S/c21-8-1-2-15(13(22)3-8)27-7-12(20(29)30)17(28)9-4-14(23)19(25-18(9)27)26-5-10-11(6-26)16(10)24;1-5(2,3)4/h1-4,7,10-11,16H,5-6,24H2,(H,29,30);1H3,(H,2,3,4)/t10-,11+,16+;

InChI key

DYNZICQDCVYXFW-AHZSKCOESA-N

Related Categories

Aplicación

Trovafloxacin mesylate has been used as a test compound in toxicity assay to assess its toxicity in 2D hepatocyte cultures.[1] It has also been used to manipulate the mechanism of apoptotic cell disassembly during apoptosis.[2]

Envase

5, 25 mg in glass bottle

Acciones bioquímicas o fisiológicas

Trovafloxacin mesylate acts as a pannexin1 (Panx1) inhibitor.[2]
Trovafloxacin mesylate is a broad spectrum antibiotic. Trovafloxacin mesylate blocks the activity of DNA gyrase and topoisomerase IV, enzymes essential in the repliction, transcription, and repair of bacterial DNA.

Otras notas

This compound was developed by Pfizer for Immunology research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Información legal

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.

pictogramas

CorrosionHealth hazard

Palabra de señalización

Danger

Frases de peligro

Clasificaciones de peligro

Repr. 2 - Skin Corr. 1B

Código de clase de almacenamiento

8B - Non-combustible, corrosive hazardous materials

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificate of Analysis

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Certificate of Origin

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