PZ0015

Trovafloxacin mesylate

>98% (HPLC)

• Synonym(s): (1α,5α,6α)-7-(6-Amino-3-azabicyclo[3.1.0]hex-3-yl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid methanesulfonate, CP-99219-27, Trovafloxacin methanesulfonate
• Empirical Formula (Hill Notation): C₂₀H₁₅F₃N₄O₃ · CH₃SO₃H
• CAS Number: 147059-75-4
• Molecular Weight: 512.46
• Número MDL: MFCD00913361
• ID de la sustancia en PubChem: 329823684
• NACRES: NA.77

Properties

• Nivel de calidad: 100
• ensayo: >98% (HPLC)
• formulario: powder
• manufacturer/tradename: Pfizer^®
• color: white to off-white
• solubilidad: DMSO: >10 mg/mL
• emisor: Pfizer
• temp. de almacenamiento: room temp
• SMILES string: CS(O)(=O)=O.NC1C2CN(CC12)c3nc4N(C=C(C(O)=O)C(=O)c4cc3F)c5ccc(F)cc5F
• InChI: 1S/C20H15F3N4O3.CH4O3S/c21-8-1-2-15(13(22)3-8)27-7-12(20(29)30)17(28)9-4-14(23)19(25-18(9)27)26-5-10-11(6-26)16(10)24;1-5(2,3)4/h1-4,7,10-11,16H,5-6,24H2,(H,29,30);1H3,(H,2,3,4)/t10-,11+,16+;
• InChI key: DYNZICQDCVYXFW-AHZSKCOESA-N

Description

Aplicación

Trovafloxacin mesylate has been used as a test compound in toxicity assay to assess its toxicity in 2D hepatocyte cultures.[1] It has also been used to manipulate the mechanism of apoptotic cell disassembly during apoptosis.[2]

Envase

5, 25 mg in glass bottle

Acciones bioquímicas o fisiológicas

Trovafloxacin mesylate acts as a pannexin1 (Panx1) inhibitor.[2]

Trovafloxacin mesylate is a broad spectrum antibiotic. Trovafloxacin mesylate blocks the activity of DNA gyrase and topoisomerase IV, enzymes essential in the repliction, transcription, and repair of bacterial DNA.

Otras notas

This compound was developed by Pfizer for Immunology research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Información legal

Sold for research purposes under agreement from Pfizer Inc.

Pfizer is a registered trademark of Pfizer, Inc.

Safety Information

• pictogramas: GHS05,GHS08
• Palabra de señalización: Danger
• Frases de peligro: H314 - H361
• Consejos de prudencia: P201 - P260 - P280 - P301 + P330 + P331 - P303 + P361 + P353 - P305 + P351 + P338
• Clasificaciones de peligro: Repr. 2 - Skin Corr. 1B
• Código de clase de almacenamiento: 8B - Non-combustible, corrosive hazardous materials
• WGK: WGK 3
• Punto de inflamabilidad F: Not applicable
• Punto de inflamabilidad C: Not applicable