S5261

Sigma-Aldrich

Sodium selenite

BioReagent, suitable for cell culture, ≥98%

Fórmula lineal:
Na2SeO3
Número de CAS:
Peso molecular:
172.94
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.75

Quality Level

biological source

synthetic (inorganic)

product line

BioReagent

assay

≥98%

form

powder

application(s)

cell culture | mammalian: suitable

mp

>350 °C (lit.)

solubility

water: 50 mg/mL, clear to very slightly hazy, colorless

SMILES string

[Na+].[Na+].[O-][Se]([O-])=O

InChI

1S/2Na.H2O3Se/c;;1-4(2)3/h;;(H2,1,2,3)/q2*+1;/p-2

InChI key

BVTBRVFYZUCAKH-UHFFFAOYSA-L

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Application

Sodium selenite is commonly used as a source of selenium in biological research, where selenium is an essential trace element that is normally provided by serum. Selenium is present in selenoproteins such as glutathione peroxidase and thioredoxin reductase, which contain the selenium analog of cysteine, selenocysteine. In particular, glutathione peroxidase has a role in detoxification in vivo as a scavenger of peroxides. Sodium selenite has been utilized in studies of cell proliferation and cancer research. It has been used to alter gene expression in HepG2 cells as analyzed by cDNA microarrays. Sodium selenite can inhibit zinc finger protein/DNA interactions. Sodium selenite has been shown to alter mitochondrial membrane potentials and thus potentially contribute to apoptosis.
This product is cell culture tested (0.005 mg/L) and is appropriate for use in cell culture applications.

Packaging

10, 25, 100 g in glass bottle

pictograms

Skull and crossbonesEnvironment

signalword

Danger

hazcat

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

Supp Hazards

EUH031

storage_class_code

6.1B - Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK Germany

WGK 2

Flash Point F

Not applicable

Flash Point C

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificado de Análisis

Certificado de origen

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