• SAB4200182
All Photos(2)



Anti-Glutathione Reductase antibody, Mouse monoclonal

clone GR6, purified from hybridoma cell culture

Anti-GR, Anti-GSR, Anti-Glutathione-disulfide reductase, Anti-NADPH:oxidized glutathione oxidoreductase
MDL number:

biological source


Quality Level



antibody form

purified from hybridoma cell culture

antibody product type

primary antibodies


GR6, monoclonal


buffered aqueous solution

mol wt

antigen ~55 kDa

species reactivity



~1.0 mg/mL


immunoprecipitation (IP): suitable
western blot: 2-4 μg/mL using whole extracts of human HepG2 cells.



UniProt accession no.

shipped in

dry ice

storage temp.


Gene Information

human ... GSR(2936)

General description

Monoclonal Anti-Glutathione Reductase (mouse IgG1 isotype) is derived from the hybridoma GR6 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a human Glutathione reductase recombinant protein. Glutathione reductase is a homodimeric enzyme containing one FAD molecule and NADPH binding domain per subunit. This gene is located on human chromosome 8p.


mice immunized with a human Glutathione reductase recombinant protein. The corresponding proteins in rat and mouse share 86% and 85% homology, respectively.


Monoclonal Anti-Glutathione Reductase antibody produced in mouse has been used in:
  • immunohistochemical
  • immunofluorescence studies
  • immunoblotting
  • immunoprecipitation

Biochem/physiol Actions

Glutathione reductase (GR) is a ubiquitous flavoenzyme involved in protecting cells from stress. GR catalyses the reduction of oxidized glutathione (GSSG) to glutathione (GSH). It is an essential component of the glutathione redox cycle, which maintains adequate levels of reduced cellular GSH. GSH serves as an antioxidant and also as an electron donor for glutathione peroxidases and a substrate for glutathione-S-transferases.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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