SAB4500088

Anti-Tubulin β antibody produced in rabbit

affinity isolated antibody

• Synonym(s): TUBB3, TUBB4, Tubulin β-3 chain, Tubulin β-4, Tubulin β-III
• Número MDL: MFCD01322746
• NACRES: NA.41

Properties

• origen biológico: rabbit
• Nivel de calidad: 100
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• antibody product type: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• mol peso: antigen 50 kDa
• species reactivity: human, mouse, rat
• concentración: ~1 mg/mL
• technique(s): ELISA: 1:5000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• Nº de acceso NCBI: Q13509
• Nº de acceso UniProt: Q13509
• enviado en: wet ice
• temp. de almacenamiento: −20°C
• Gene Information: human ... TUBB3(10381)

Description

Descripción general

Tubulin β-III (TUBB3) is a constituent of microtubules. It is expressed in mature neurons. It is located on human chromosome 16q24.

Anti-Tubulin β Antibody detects endogenous levels of total Tubulin β protein.

Inmunógeno

The antiserum was produced against synthesized peptide derived from human Tubulin beta.

Immunogen Range: 401-450

Aplicación

Anti-Tubulin β C-Terminal antibody has been used in immunoblot assays.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunocytochemistry (1 paper)

Envase

100 μg

Acciones bioquímicas o fisiológicas

Upregulation of tubulin β-III (TUBB3) shows vigorous tumor characteristics and genetic instability in urinary bladder cancer. It participates in the separation of chromosome. Individuals with congenital fibrosis of the extraocular muscle type 3 (CFEOM3) show mutations in TUBB3. βIII-tubulin modulates glucose metabolism, thereby transforms glucose starvation stress signaling to develop the multiplication of cell and survival in non-small cell lung cancer cells.

Características y beneficios

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Forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• WGK: nwg
• Punto de inflamabilidad F: Not applicable
• Punto de inflamabilidad C: Not applicable