Merck
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SAB4502211

Sigma-Aldrich

Anti-PLK1 antibody produced in rabbit

affinity isolated antibody

Synonym(s):
PLK-1, Polo-like kinase 1, STPK13, Serine/threonine-protein kinase 13
Número MDL:
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

100

conjugado

unconjugated

forma del anticuerpo

affinity isolated antibody

antibody product type

primary antibodies

clon

polyclonal

formulario

buffered aqueous solution

mol peso

antigen 68 kDa

species reactivity

rat, mouse, human

concentración

~1 mg/mL

technique(s)

ELISA: 1:20000
immunofluorescence: 1:100-1:500
western blot: 1:500-1:1000

Nº de acceso NCBI

Nº de acceso UniProt

enviado en

wet ice

temp. de almacenamiento

−20°C

Gene Information

human ... PLK1(5347)

Descripción general

Anti-PLK1 Antibody detects endogenous levels of total PLK1 protein.
PLK1 (polo like kinase 1) gene is mapped to human chromosome 16p12.2. It codes for the protein serine/threonine kinase.

Inmunógeno

The antiserum was produced against synthesized peptide derived from human PLK1.

Immunogen Range: 176-225

Acciones bioquímicas o fisiológicas

PLK1 (polo like kinase 1) is predominantly involved in mitosis. It mediates the phosphorylation of cyclin B1/CDK1 (cyclin dependent kinase 1) complex, and activation of the anaphase promoting complex. PLK1 has anti-apoptotic function. Upregulation of gene is observed in different types of cancer, such as colorectal cancer and is regarded as an oncogene. PLK1 is involved in checkpoint recovery and adaptation following DNA damage.

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Código de clase de almacenamiento

12 - Non Combustible Liquids

WGK

nwg

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificate of Analysis

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Certificate of Origin

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