SAB5700288

Sigma-Aldrich

Anti-Phospho-ATF2-T71 antibody produced in rabbit

Sinónimos:
ATF2, CREB-2, CREB2, TREB7, CRE-BP1, HB16
En este momento no podemos mostrarle ni los precios ni la disponibilidad

biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

13- 15
23-24
35-54

species reactivity

mouse, rat, human

concentration

3.24 mg/ml

application(s)

immunofluorescence: 1:50-1:100
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... ATF2(1386)

General description

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell′s DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene

Immunogen

A synthetic phosphorylated peptide around T71 of human ATF2 (NP_001871.2).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

WGK Germany

WGK 1

Flash Point F

Not applicable

Flash Point C

Not applicable

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