Merck
  • SAB5700364
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SAB5700364

Sigma-Aldrich

Anti-Phospho-p53-S46 antibody produced in rabbit

Synonym(s):
BCC7, BMFS5, LFS1, P53, TP53, TRP53, p53

biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

23-43

species reactivity

human

concentration

0.33 mg/ml

technique(s)

immunoprecipitation (IP): 1:50-1:100
western blot: 1:1000-1:2000

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... TP53(7157)

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This Item
SAB5700559SAB5700558SAB5701828
biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

-

clone

polyclonal

clone

polyclonal

clone

polyclonal

clone

monoclonal

form

buffered aqueous solution

form

buffered aqueous solution

form

buffered aqueous solution

form

liquid

mol wt

23-43

mol wt

43

mol wt

43

mol wt

-

species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

rat, human, mouse

General description

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277).

Immunogen

A synthetic phosphorylated peptide around S46 of human p53 (NP_000537.3).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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