SAB5700396

Sigma-Aldrich

Anti-Phospho-RPS6-S235/236 antibody produced in rabbit

Sinónimos:
S6, RPS6
En este momento no podemos mostrarle ni los precios ni la disponibilidad

biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

28

species reactivity

mouse, rat, human

concentration

0.65 mg/ml

application(s)

western blot: 1:500-1:2000

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... RPS6(6194)

General description

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Immunogen

A synthetic phosphorylated peptide around S235 & S236 of human RPS6 (NP_001001.2).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

WGK Germany

WGK 1

Flash Point F

Not applicable

Flash Point C

Not applicable

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