SAB5700826

Sigma-Aldrich

Anti-RAD51 antibody produced in rabbit

Sinónimos:
BRCC5, FANCR, HsT16930, MRMV2, RAD51A, RAD51, HsRad51, HRAD51, RECA
En este momento no podemos mostrarle ni los precios ni la disponibilidad

biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

26
31
36

species reactivity

human, rat, mouse

concentration

5.22 mg/ml

application(s)

western blot: 1:500-1:1000

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... RAD51(5888)

General description

The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human RAD51 (NP_002866.2).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

WGK Germany

WGK 1

Flash Point F

Not applicable

Flash Point C

Not applicable

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