SBPVR3

Sigma-Aldrich

SB PREDIVEZ Reagent Kit for MRP2, MRP3, and MRP5

En este momento no podemos mostrarle ni los precios ni la disponibilidad

recombinant

expressed in human cells

form

liquid

shipped in

dry ice

storage temp.

−70°C

General description

SOLVO Biotechnology offers ready-to-use assay kits for efflux and uptake transporters. SOLVO′s PREDIVEZ Vesicular Transport Assay Kits are suitable for efflux transporter inhibition studies. The kits are designed to test the inhibitory effect of one or more test compounds on the vesicular transport of a probe substrate. In most cases a fluorescent probe substrate is included. Kits contain all reagents and solutions necessary to conduct the drug-transporter interaction assay of need.

Application

The PREDIVEZ Vesicular Transport Kit is a simple and powerful tool to investigate drug transporter interactions. It provides information on any interaction between the ABC transporter and the drug candidate that would affect the transport of the fluorescent or radiolabeled or cold.

PREDIVEZ vesicular transport kits contains buffers, probe substrate, and reference inhibitors needed to run vesicular transport assays (sufficient for 300 wells/kit –equivalent to existing 9-cpd PV kits). Assay protocol, calculation template, and example data file available on SOLVO
website.

Transport membranes and control membranes are sold separately. This PREDIVEZ vesicular transport kit requires the transporter membranes and corresponding control membrane below:

SB-MRP2-Sf9-VT MRP2 human membrane vesicles part number SBVT05-1EA and corresponding control membrane SB-beta-gal-Sf9-CTRL part number SBCT03-1EA

SB-MRP2-HEK293-VT MRP2 human membrane vesicles part number SBVT14-1EA and corresponding control membrane SB-HEK293-Mock-CTRL part number SBCT06-1EA

SB-MRP3-Sf9-VT MRP3 human membrane vesicles part number SBVT06-1EA and corresponding control membrane SB-beta-gal-Sf9-CTRL part number SBCT03-1EA

SB-MRP3-HEK293-VT MRP3 human membrane vesicles part number SBVT15-1EA and corresponding control membrane SB-HEK293-Mock-CTRL part number SBCT06-1EA

SB-MRP5-HEK293-VT MRP5 human membrane vesicles part number SBVT08-1EA and corresponding control membrane SB-HEK293-Mock-CTRL part number SBCT06-1EA

Legal Information

PREDIVEZ is a trademark of Solvo Biotechnology

pictograms

Corrosion

signalword

Danger

Flash Point F

188.6 °F

Flash Point C

87 °C

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