SCP0013

Sigma-Aldrich

Allatostatin B2 cockroach

Empirical Formula (Hill Notation):
C104H150N24O27
Peso molecular:
2168.45
NACRES:
NA.32
En este momento no podemos mostrarle ni los precios ni la disponibilidad

assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥75%

storage condition

protect from light

storage temp.

−20°C

Amino Acid Sequence

Ala-Tyr-Ser-Tyr-Val-Ser-Glu-Tyr-Lys-Arg-Leu-Pro-Val-Tyr-Asn-Phe-Gly-Leu-NH2

Application

Allatostatins are insect and crustacean neuropeptides that inhibit juvenile hormone and reduce food intake. Allostatin B2 (cricket-type), a myoinhibitory peptide (MIP), is used to study the regulation of juvenile hormone production and as a target for insecticide development.

WGK Germany

WGK 3

Flash Point F

Not applicable

Flash Point C

Not applicable

Certificado de Análisis
Theresa M Szabo et al.
The Journal of comparative neurology, 519(13), 2658-2676 (2011-04-15)
The crustacean stomatogastric ganglion (STG) is modulated by a large number of amines and neuropeptides that are found in descending pathways from anterior ganglia or reach the STG via the hemolymph. Among these are the allatostatin (AST) B types, also...
Julia Schulze et al.
The Journal of comparative neurology, 520(5), 1078-1097 (2011-11-19)
Myoinhibitory peptides (MIPs) are a family of insect W(X(6))Wamides with inhibitory effects on visceral muscles and juvenile hormone synthesis. Although MIPs are widely distributed within the nervous system, a detailed analysis of their distribution and function in insect brains is...
M Williamson et al.
Biochemical and biophysical research communications, 281(2), 544-550 (2001-02-22)
The insect allatostatins obtained their names because they block the biosynthesis of juvenile hormone (a terpenoid) in the corpora allata (two endocrine organs near the insect brain). Chemically, the allatostatins can be subdivided into three different peptide groups: the A-type...
N Audsley et al.
Journal of insect physiology, 54(6), 969-980 (2008-04-02)
Allatoregulatory peptides either inhibit (allatostatins) or stimulate (allatotropins) juvenile hormone (JH) synthesis by the corpora allata (CA) of insects. However, these peptides are pleitropic, the regulation of JH biosynthesis is not their only function. There are currently three allatostatin families...

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