Merck
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SCP0095

Sigma-Aldrich

Caspase Inhibitor

≥95% (HPLC)

Synonym(s):
Ac-LEHD-CHO, caspase 9 inhibitor
Empirical Formula (Hill Notation):
C23H34N6O9
Molecular Weight:
538.55
NACRES:
NA.32

ensayo

≥95% (HPLC)

formulario

lyophilized

composición

Peptide Content, ≥80%

condiciones de almacenamiento

protect from light

temp. de almacenamiento

−20°C

Gene Information

human ... CASP9(842)

Amino Acid Sequence

Ac-Leu-Glu-His-Asp-al

Acciones bioquímicas o fisiológicas

Ac-Leu-Glu-His-Asp-al, or Ac-LEHD-CHO, is a cell-permeable tetrapeptide aldehyde. It is an inhibitor of caspase-9.[1][2] Its target of action has been proposed to be the mitochondrial pathway of apoptosis. Ac-LEHD-CHO has also been postulated to prevent cleavage of caspase-8, and partly to prevent cleavage of caspase-3.

Código de clase de almacenamiento

11 - Combustible Solids

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificate of Analysis

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Certificate of Origin

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