SMB00705

Sigma-Aldrich

Sesamin

≥98% (HPLC)

Sinónimos:
Fagarol
Empirical Formula (Hill Notation):
C20H18O6
Número de CAS:
Peso molecular:
354.35
MDL number:
NACRES:
NA.25
En este momento no podemos mostrarle ni los precios ni la disponibilidad

Quality Level

assay

≥98% (HPLC)

form

powder

solubility

DMSO: 10 mg/mL

storage temp.

−20°C

SMILES string

C1Oc2ccc(cc2O1)[C@H]3OC[C@H]4[C@@H]3CO[C@@H]4c5ccc6OCOc6c5

InChI

1S/C20H18O6/c1-3-15-17(25-9-23-15)5-11(1)19-13-7-22-20(14(13)8-21-19)12-2-4-16-18(6-12)26-10-24-16/h1-6,13-14,19-20H,7-10H2/t13-,14-,19+,20+/m0/s1

InChI key

PEYUIKBAABKQKQ-AFHBHXEDSA-N

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Categorías relacionadas

Biochem/physiol Actions

Sesamin is the most abundant lignan in sesame seeds. It presents multiple health benefits including hypocholesterolemic activity, antihypertensive effect, anticarcinogenic potential, antiaging effect, immunoregulatory activity, hypoglycemic action, antithrombotic activity, hepatoprotective effect and antioxidant activity. Sesamin has also been demonstrated to work synergistically with vitamin E against lipid peroxidation. Sesamin was found to be metabolized into several catechol forms in the liver. These cathecols have a potent ability to scavenge superoxide radicals.
Non-competitive Δ5-desaturase inhibitor.

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point F

Not applicable

Flash Point C

Not applicable

Mitsuo Namiki
Critical reviews in food science and nutrition, 47(7), 651-673 (2007-10-19)
The results of recent food chemical and nutraceutical studies on the traditionally well-known health value of sesame are described, including some aspects of the utilization of sesame. The highly antioxidative activity of sesame oil was clarified and found to involve...
Yun-Ping Lim et al.
Evidence-based complementary and alternative medicine : eCAM, 2012, 242810-242810 (2012-05-31)
Inconsistent expression and regulation of drug-metabolizing enzymes (DMEs) are common causes of adverse drug effects in some drugs with a narrow therapeutic index (TI). An important cytochrome, cytochrome P450 3A4 (CYP3A4), is predominantly regulated by a nuclear receptor, pregnane X...
Kaori Yasuda et al.
Expert opinion on drug metabolism & toxicology, 8(1), 93-102 (2011-11-22)
Sesamin is a major lignan found in sesame and is known to have various biological effects. Some of these biological effects occur following its metabolic conversion to corresponding catechols and, therefore, the study of sesamin metabolism is quite important. There...

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