Merck
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SML0012

Sigma-Aldrich

SBE 13 hydrochloride

≥98% (HPLC)

Synonym(s):
N-(4-((6-Chloro-3-pyridinyl)methoxy)-3-methoxybenzyl)-N-(2-(3,4-dimethoxyphenyl)ethyl)amine; N-[[4-[(6-Chloro-3-pyridinyl)methoxy]-3-methoxyphenyl]methyl]-3,4-dimethoxy-benzeneethanamine hydrochloride
Empirical Formula (Hill Notation):
C24H27ClN2O4·HCl
CAS Number:
Molecular Weight:
479.40
Número MDL:
ID de la sustancia en PubChem:
NACRES:
NA.77

Nivel de calidad

100

ensayo

≥98% (HPLC)

formulario

powder

color

white to tan

solubilidad

DMSO: ≥17 mg/mL

temp. de almacenamiento

2-8°C

SMILES string

Cl.COc1ccc(CCNCc2ccc(OCc3ccc(Cl)nc3)c(OC)c2)cc1OC

InChI

1S/C24H27ClN2O4.ClH/c1-28-20-7-4-17(12-22(20)29-2)10-11-26-14-18-5-8-21(23(13-18)30-3)31-16-19-6-9-24(25)27-15-19;/h4-9,12-13,15,26H,10-11,14,16H2,1-3H3;1H

InChI key

QBGSVDJLQQXEGG-UHFFFAOYSA-N

Aplicación

SBE 13 hydrochloride may be used in cell signaling studies.

Envase

5, 25 mg in glass bottle

Acciones bioquímicas o fisiológicas

SBE13 is a cell-permeable highly potent polo-like kinase (Plk1) inhibitor that targets the inactive conformation of the kinase. SBE13 does not effect the activity of Plk2, Plk3, Aurora A kinases.

Certificate of Analysis

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Certificate of Origin

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