Merck
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SML0370

Sigma-Aldrich

Kartogenin

≥98% (HPLC)

Synonym(s):
KGN, 2-[(Biphenyl-4-yl)carbamoyl]benzoic acid, 4′-Phenyl-phthalanilic acid (8CI)
Empirical Formula (Hill Notation):
C20H15NO3
CAS Number:
Molecular Weight:
317.34
Número MDL:
ID de la sustancia en PubChem:
NACRES:
NA.77

Nivel de calidad

100

ensayo

≥98% (HPLC)

formulario

powder

solubilidad

DMSO: >15 mg/mL

temp. de almacenamiento

room temp

SMILES string

O=C(NC1=CC=C(C2=CC=CC=C2)C=C1)C(C=CC=C3)=C3C(O)=O

InChI

1S/C20H15NO3/c22-19(17-8-4-5-9-18(17)20(23)24)21-16-12-10-15(11-13-16)14-6-2-1-3-7-14/h1-13H,(H,21,22)(H,23,24)

InChI key

SLUINPGXGFUMLL-UHFFFAOYSA-N

Envase

5, 25 mg in glass bottle

Acciones bioquímicas o fisiológicas

Kartogenin induces the selective differentiation of multipotent mesenchymal stem cells (MSCs) into chondrocytes. Kartogenin binds to filamin A, and disrupts the specific interaction between filamin A and CBFβ (core-binding factor β subunit). Apparently, kartogenin induces chondrogenesis by regulating the nuclear localization of CBFβ.
Kartogenin is a small heterocyclic compound. It is involved in regulating runt-related transcription factor 1 (RUNX1), which plays an important role in chondrocyte proliferation and survival.

Código de clase de almacenamiento

11 - Combustible Solids

WGK

WGK 3

Certificate of Analysis

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Certificate of Origin

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