SML0550

Nestorone

≥97% (HPLC)

• Sinónimos: ST-1435, 17-(Acetyloxy)-16-methylene-19-norpregn-4-ene-3,20-dione, Nestoron, Elcometrine, 17-Hydroxy-16-methylene-19-norpregn-4-ene-3,20-dione acetate, ST1435
• Empirical Formula (Hill Notation): C₂₃H₃₀O₄
• Número de CAS: 7759-35-5
• Peso molecular: 370.48
• MDL number: MFCD01711303
• PubChem Substance ID: 329825546
• NACRES: NA.77

Propiedades

• Quality Level: 100
• assay: ≥97% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 5 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: CC(=O)OC@1(C(C)=O)C(=C)CC@H2C@@H3CCC4=CC(=O)CCC@@H4C@H3CCC@12C
• InChI: 1S/C23H30O4/c1-13-11-21-20-7-5-16-12-17(26)6-8-18(16)19(20)9-10-22(21,4)23(13,14(2)24)27-15(3)25/h12,18-21H,1,5-11H2,2-4H3/t18-,19+,20+,21-,22-,23-/m0/s1
• InChI key: CKFBRGLGTWAVLG-GOMYTPFNSA-N
• Gene Information: human ... PGR(5241)

Descripción

Packaging

10, 50 mg in glass bottle

Biochem/physiol Actions

Nestorone is a potent progesterone receptor agonist with no androgenic, estrogenic, or glucocorticoid-like activities. Nestorone has been used as a female contraceptive, and recent studies inidicate that it may be useful as a male contraceptive as well. It has also been shown to have neurogenic and neuroprotective activity.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC^®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Información de seguridad

• RIDADR: NONH for all modes of transport
• WGK Germany: WGK 3
• Flash Point F: Not applicable
• Flash Point C: Not applicable