Merck
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SML0593

Sigma-Aldrich

CGP52432

≥98% (HPLC)

Synonym(s):
[3-[[(3,4-Dichlorophenyl)methyl]amino]propyl](diethoxymethyl)-phosphinic acid
Empirical Formula (Hill Notation):
C15H24Cl2NO4P
CAS Number:
Molecular Weight:
384.24
NACRES:
NA.77

Nivel de calidad

100

ensayo

≥98% (HPLC)

formulario

powder

condiciones de almacenamiento

desiccated

color

white to beige

solubilidad

H2O: 1 mg/mL, clear (warmed)

temp. de almacenamiento

2-8°C

InChI

1S/C15H24Cl2NO4P/c1-3-21-15(22-4-2)23(19,20)9-5-8-18-11-12-6-7-13(16)14(17)10-12/h6-7,10,15,18H,3-5,8-9,11H2,1-2H3,(H,19,20)

InChI key

GJZVQXWEIYRHBE-UHFFFAOYSA-N

Aplicación

CGP52432 has been used as a γ-aminobutyric acid B (GABAB) antagonist:
  • to study its effects on the simulation of the onset of status epilepticus (SE) in mice
  • for voltage-clamp recording in mice neurons
  • to study its effects on the GABAB receptor-mediated neurotransmission in guinea pig hippocampus

Envase

5, 25 mg in glass bottle

Acciones bioquímicas o fisiológicas

CGP52432 participates in inhibiting the glycine overflow in the hippocampus.
CGP52432 is a very potent antagonist of GABAB receptors. (IC50 = 85 nM).

Características y beneficios

This compound is featured on the GABAB Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Otras notas

Do not freeze.

Código de clase de almacenamiento

11 - Combustible Solids

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificate of Analysis

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Certificate of Origin

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