Merck
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SML0598

Sigma-Aldrich

SDZ 220-581 hydrochloride

≥98% (HPLC)

Synonym(s):
(S)-α-Amino-2-chloro-5-(phosphonomethyl)[1,1-biphenyl]-3-propanoic acid hydrochloride
Empirical Formula (Hill Notation):
C16H17ClNO5P · HCl
CAS Number:
Molecular Weight:
406.20
Número MDL:
ID de la sustancia en PubChem:
NACRES:
NA.77

Nivel de calidad

100

ensayo

≥98% (HPLC)

formulario

powder

actividad óptica

[α]/D -5 to -8°, c = 1 in 1 M HCl

color

white to beige

solubilidad

DMSO: 5 mg/mL, clear (warmed)

temp. de almacenamiento

room temp

SMILES string

OC([C@@H](N)CC1=CC(C2=CC=CC=C2Cl)=CC(CP(O)(O)=O)=C1)=O.Cl

InChI

1S/C16H17ClNO5P.ClH/c17-14-4-2-1-3-13(14)12-6-10(8-15(18)16(19)20)5-11(7-12)9-24(21,22)23;/h1-7,15H,8-9,18H2,(H,19,20)(H2,21,22,23);1H/t15-;/m0./s1

InChI key

WSYIMHDAUSNYSF-RSAXXLAASA-N

Envase

5, 25 mg in glass bottle

Acciones bioquímicas o fisiológicas

SDZ 220-581 is a competitive NMDA receptor antagonist that penetrates the blood brain barrier. ISDZ 220-581 selectively blocks the glutamate recognition-site of the NMDA receptor and reduces prepulse inhibition (PPI). SDZ 220-581 reduces prepulse inhibition (PPI) and has an ED50 of less than 3.2 mg/kg for protection against MES-induced seizures.

pictogramas

Exclamation mark

Palabra de señalización

Warning

Frases de peligro

Consejos de prudencia

Clasificaciones de peligro

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órganos de actuación

Respiratory system

Código de clase de almacenamiento

13 - Non Combustible Solids

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificate of Analysis

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Certificate of Origin

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