Merck
All Photos(1)

SML0826

Sigma-Aldrich

FH1

≥98% (HPLC)

Synonym(s):
NSC 12407, N,N′-(Methylenedi-4,1-phenylene)bis-acetamide, BRD-K4477, N,N′-(Methylenedi-4,1-phenylene)diacetamide
Empirical Formula (Hill Notation):
C17H18N2O2
CAS Number:
Molecular Weight:
282.34
NACRES:
NA.77

Nivel de calidad

100

ensayo

≥98% (HPLC)

formulario

powder

color

white to beige

solubilidad

DMSO: 10 mg/mL, clear (warmed)

temp. de almacenamiento

2-8°C

InChI

1S/C17H18N2O2/c1-12(20)18-16-7-3-14(4-8-16)11-15-5-9-17(10-6-15)19-13(2)21/h3-10H,11H2,1-2H3,(H,18,20)(H,19,21)

InChI key

OEXMNSOPAKOPEF-UHFFFAOYSA-N

Envase

5, 25 mg in glass bottle

Acciones bioquímicas o fisiológicas

FH1 (BRD-K4477) was found to enhance hepatocyte functions and promote the differentiation of induced pluripotent stem cell–derived hepatocytes toward a more mature phenotype than what had previouslybeen obtainable. Human induced pluripotent stem (iPS) cells that are differentiated toward hepatocyte-like (iHep) cells typically show an immature hepatic phenotype and have limited use as a renewable source of functional human hepatocytes. Cultures treated with both FH1 (BRD-K4477) and another compound that induces proliferation, FPH1 (BRD-6125), contained larger colonies of iHep cells, which showed more pronounced hepatocyte morphologies with a more mature phenotype than previously obtainable.

pictogramas

Environment

Palabra de señalización

Warning

Frases de peligro

Consejos de prudencia

Clasificaciones de peligro

Aquatic Acute 1

Código de clase de almacenamiento

13 - Non Combustible Solids

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificate of Analysis

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Certificate of Origin

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