Merck
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SML0986

Sigma-Aldrich

Divin

≥98% (HPLC)

Synonym(s):
N′-[(E)-(2-Hydroxynaphthalen-1-yl)methylidene]-3-(2-methyl-1H-benzimidazol-1-yl)propanehydrazide), 2-[(2-Hydroxy-1-naphthalenyl)methylene]hydrazide-2-methyl-1H-Benzimidazole-1-propanoic acid
Empirical Formula (Hill Notation):
C22H20N4O2
CAS Number:
Molecular Weight:
372.42
NACRES:
NA.77

Nivel de calidad

100

ensayo

≥98% (HPLC)

formulario

powder

color

white to beige

solubilidad

DMSO: 20 mg/mL, clear

temp. de almacenamiento

2-8°C

Descripción general

Divin is formed by minicell locus C (minC) and minD gene products. Divin is a nonspecific inhibitor of septation. It has an ability to inhibit cell division at all potential division sites.

Envase

5, 25 mg in glass bottle

Acciones bioquímicas o fisiológicas

Divin (DIVision Inhibitor) is an inhibitor of bacterial division with a novel mechanism of action. During bacterial division, more than a dozen different proteins assemble at the division site in a specific order to form a complex called the divisome, with the first protein, FtsZ , followed by ‘early′ or ‘late′ proteins based on their temporal localization. Divin blocks cell division by disrupting the spatial and temporal localization of the late division proteins, disrupting their assembly and preventing compartmentalization of the cytoplasm. Divin has been found to be a potent bacteriostatic agent against clinical pathogens with low toxicity against mammalian cells.

Código de clase de almacenamiento

13 - Non Combustible Solids

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificate of Analysis

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Certificate of Origin

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