Merck
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SML1029

Sigma-Aldrich

KP372-1

≥98% (HPLC)

Synonym(s):
10H-Indeno[2,1-e]tetrazolo[1,5-b][1,2,4]triazin-10-one (1:1), 6H-Indeno[1,2-e]tetrazolo[1,5-b][1,2,4]triazin-6-one
Empirical Formula (Hill Notation):
C10H4N6O
CAS Number:
Molecular Weight:
224.18
NACRES:
NA.77

descripción

1:1 mixture of two isomers

Nivel de calidad

100

ensayo

≥98% (HPLC)

formulario

powder

color

light yellow to dark yellow

solubilidad

DMSO: 10 mg/mL, clear

temp. de almacenamiento

2-8°C

Envase

5, 25 mg in glass bottle

Acciones bioquímicas o fisiológicas

KP372-1 is a potent inhibitor of AKT and PKD. KP-372-1 blocks PI3K/AKT/mTOR signaling pathways, and induces apoptosis in leukemia cell lines and primary tumor cells from patients with AML.

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