Merck
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SML1324

Sigma-Aldrich

XEN445

≥98% (HPLC)

Synonym(s):
(S)-2-(3-(Pyridin-2-ylmethoxy)pyrrolidin-1-yl)-5-(trifluoromethyl)benzoic acid
Empirical Formula (Hill Notation):
C18H17F3N2O3
CAS Number:
Molecular Weight:
366.33

Nivel de calidad

100

ensayo

≥98% (HPLC)

formulario

powder

color

white to beige

solubilidad

DMSO: 10 mg/mL, clear

temp. de almacenamiento

2-8°C

Envase

5, 25 mg in glass bottle

Acciones bioquímicas o fisiológicas

XEN445 is a potent and selective inhibitor of endothelial lipase with an IC50 of 237 nM and high selectivity over hepatic and lipoprotein lipases. In experiments with wild-type mice, XEN445 raised plasma HDL-cholesterol levels by 16% after 3 days and by 30% after 9 days dosing.

Código de clase de almacenamiento

11 - Combustible Solids

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificate of Analysis

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Certificate of Origin

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