Merck
All Photos(1)

SML1360

Sigma-Aldrich

Cariporide

≥98% (HPLC)

Synonym(s):
HOE-642, N-(Aminoiminomethyl)-4-(1-methylethyl)-3-(methylsulfonyl)-benzamide, N-(Diaminomethylene)-4-isopropyl-3-(methylsulfonyl)benzamide
Empirical Formula (Hill Notation):
C12H17N3O3S
CAS Number:
Molecular Weight:
283.35
ID de la sustancia en PubChem:
NACRES:
NA.77

Nivel de calidad

100

ensayo

≥98% (HPLC)

formulario

powder

color

white to beige

solubilidad

DMSO: 20 mg/mL, clear

temp. de almacenamiento

2-8°C

SMILES string

NC(NC(C1=CC(S(C)(=O)=O)=C(C(C)C)C=C1)=O)=N

InChI

1S/C12H17N3O3S/c1-7(2)9-5-4-8(11(16)15-12(13)14)6-10(9)19(3,17)18/h4-7H,1-3H3,(H4,13,14,15,16)

InChI key

IWXNYAIICFKCTM-UHFFFAOYSA-N

Envase

5, 25 mg in glass bottle

Acciones bioquímicas o fisiológicas

Cariporide is a selective inhibitor of the Na+/H+ exchanger subtype 1 (NHE-1), also known as the Na+/H+ antiporter. Cariporide has shown cardioprotective and antiarrhythmic effects, and has recently been investigated for anticancer activity.
Cariporide, a sodium-hydrogen exchange inhibitor[1] can decrease the liberation of myoglobin at the time of ischemia/reperfusion and reduces the liberation of NE (norepinephrine) during ischemia.[2]

Código de clase de almacenamiento

11 - Combustible Solids

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificate of Analysis

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Certificate of Origin

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