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SML1373

Sigma-Aldrich

Angiotensin A trifluoroacetate salt

≥98% (HPLC)

Synonym(s):
ARVYIHPF trifluoroacetate salt, Ala-Arg-Val-Tyr-Ile-His-Pro-Phe trifluoroacetate salt, Ang A trifluoroacetate salt
Empirical Formula (Hill Notation):
C49H71N13O10 · xC2HF3O2
CAS Number:
Molecular Weight:
1002.17 (free base basis)
ID de la sustancia en PubChem:
NACRES:
NA.77

Nivel de calidad

100

ensayo

≥98% (HPLC)

formulario

powder

color

white to off-white

temp. de almacenamiento

−20°C

SMILES string

[H]N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@H](C(N[C@]([C@@H](C)CC)([H])C(N[C@H](C(N1CCC[C@H]1C(N[C@H](C(O)=O)CC2=CC=CC=C2)=O)=O)CC3=CN=CN3)=O)=O)CC(C=C4)=CC=C4O)=O)=O)=O)C

InChI

1S/C49H71N13O10/c1-6-28(4)40(46(69)58-36(24-32-25-53-26-55-32)47(70)62-21-11-15-38(62)44(67)59-37(48(71)72)23-30-12-8-7-9-13-30)61-43(66)35(22-31-16-18-33(63)19-17-31)57-45(68)39(27(2)3)60-42(65)34(56-41(64)29(5)50)14-10-20-54-49(51)52/h7-9,12-13,16-19,25-29,34-40,63H,6,10-11,14-15,20-24,50H2,1-5H3,(H,53,55)(H,56,64)(H,57,68)(H,58,69)(H,59,67)(H,60,65)(H,61,66)(H,71,72)(H4,51,52,54)/t28-,29-,34-,35-,36-,37-,38-,39-,40-/m0/s1

InChI key

CHCOFDZSJYMQMX-NOQNJSOHSA-N

Envase

5, 25 mg in glass bottle

Acciones bioquímicas o fisiológicas

Angiotensin A (Ang A) is an endogenous vasoconstrictor octapeptide. It is a derivative of angiotensin II (Ang II) that differs from Ang II in having alanine instead of aspartic acid as the first amino acid. Angiotensin A has similar affinity as Angiotensin II for AT1 and AT2 receptors with Ki values of 1.6 and 2.3 nM at AT1 and AT2 receptors.

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