Merck
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SML1399

Sigma-Aldrich

CCT031374 hydrobromide

≥98% (HPLC)

Synonym(s):
1-[1,1′-Biphenyl]-4-yl-2-(2,3-dihydro-9H-imidazo[1,2-a]benzimidazol-9-yl)ethanone hydrobromide
Empirical Formula (Hill Notation):
C23H19N3O · HBr
CAS Number:
Molecular Weight:
434.33
Número MDL:
ID de la sustancia en PubChem:
NACRES:
NA.77

Nivel de calidad

100

ensayo

≥98% (HPLC)

formulario

powder

condiciones de almacenamiento

desiccated

color

white to beige

solubilidad

DMSO: 10 mg/mL, clear

temp. de almacenamiento

2-8°C

SMILES string

O=C(C1=CC=C(C2=CC=CC=C2)C=C1)CN3C4=C(C=CC=C4)N5C3=NCC5.[H]Br

InChI

1S/C23H19N3O.BrH/c27-22(19-12-10-18(11-13-19)17-6-2-1-3-7-17)16-26-21-9-5-4-8-20(21)25-15-14-24-23(25)26;/h1-13H,14-16H2;1H

InChI key

MPILENOYNNNGKO-UHFFFAOYSA-N

Envase

5, 25 mg in glass bottle

Acciones bioquímicas o fisiológicas

CCT031374 is an inhibitor of TCF-dependent transcription. CCT031374 is a selective β-catenin signaling inhibitor that decreases the intracellular/soluble β-cat level. CCT031374 inhibits  proliferation of numberous cancer cell lines by induction of apoptosis.

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