Merck
All Photos(1)

SML1489

Sigma-Aldrich

FICZ

≥95% (HPLC)

Synonym(s):
6-Formylindolo[3,2-b]carbazole, 5,11-Dihydro-indolo[3,2-b]carbazole-6-carboxaldehyde
Empirical Formula (Hill Notation):
C19H12N2O
CAS Number:
Molecular Weight:
284.31
NACRES:
NA.77

Nivel de calidad

100

ensayo

≥95% (HPLC)

formulario

lyophilized powder

color

yellow

solubilidad

DMSO: 0.5 mg/mL, clear (warmed)

temp. de almacenamiento

−20°C

Envase

1, 5 mg in glass bottle

Acciones bioquímicas o fisiológicas

FICZ is a potent high affinity ligand of the aryl hydrocarbon receptor (AhR), which is a ligand-activated transcription factor that activates the expression of aromatic hydrocarbon metabolizing enzyme genes such as the CYP1A1 gene and has also been shown to have multiple additional roles in cell-cycle regulation, development and maturation of many tissues, control of inflammation, and immune response. FICZ is a photoproduct of tryptophan and is believed to be an endogenous AhR ligand. It is extremely potent, with a Kd value of 0.07 nM.
FICZ (6-formylindolo(3,2b)carbazole) being a photooxidation product of tryptophan, might serve as a chemical messenger of light.

pictogramas

Exclamation mark

Palabra de señalización

Warning

Frases de peligro

Consejos de prudencia

Clasificaciones de peligro

Acute Tox. 4 Oral

Código de clase de almacenamiento

13 - Non Combustible Solids

WGK

WGK 1

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service