Merck
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SML1493

Sigma-Aldrich

Suprafenacine

≥98% (HPLC)

Synonym(s):
SRF, 4,5,6,7-Tetrahydro-1H-indazole-3-carboxylic acid (2E)-2-[(4-methylphenyl)methylene]hydrazide, 4,5,6,7-Tetrahydro-1H-indazole-3-carboxylic acid [1p-tolyl-meth-(E)-ylidene]-hydrazide
Empirical Formula (Hill Notation):
C16H18N4O
CAS Number:
Molecular Weight:
282.34
NACRES:
NA.77

Nivel de calidad

100

ensayo

≥98% (HPLC)

formulario

powder

condiciones de almacenamiento

desiccated

color

white to beige

solubilidad

DMSO: 10 mg/mL, clear

temp. de almacenamiento

2-8°C

Envase

5, 25 mg in glass bottle

Acciones bioquímicas o fisiológicas

Suprafenacine is a cell permeable and potent microtubule destabilizing agent that induces cell cycle arrest in the G2/M phase and apoptotic cell death. Suprafenacine binds to microtubules at the colchicine-binding and inhibits polymerization. Suprafenacine is selective for cancer cells including drug-resistant cancer cells. Apparently, Suprafenacine bypasses the multidrug resistance transporter P-glycoprotein (PGP).

Código de clase de almacenamiento

13 - Non Combustible Solids

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificate of Analysis

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Certificate of Origin

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